Yuan ZM - Search Results

1

The p53 inhibitors MDM2/MDMX complex is required for control of p53 activity in vivo.

Huang L, Yan Z, Liao X, Li Y, Yang J, Wang ZG, Zuo Y, Kawai H, Shadfan M, Ganapathy S, Yuan ZM. Huang L, et al. Among authors: yuan zm. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12001-6. doi: 10.1073/pnas.1102309108. Epub 2011 Jul 5. Proc Natl Acad Sci U S A. 2011. PMID: 21730163 Free PMC article.

2

An EZH2-mediated epigenetic mechanism behind p53-dependent tissue sensitivity to DNA damage.

Kuser-Abali G, Gong L, Yan J, Liu Q, Zeng W, Williamson A, Lim CB, Molloy ME, Little JB, Huang L, Yuan ZM. Kuser-Abali G, et al. Among authors: yuan zm. Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):3452-3457. doi: 10.1073/pnas.1719532115. Epub 2018 Mar 14. Proc Natl Acad Sci U S A. 2018. PMID: 29540569 Free PMC article.

3

Critical contribution of the MDM2 acidic domain to p53 ubiquitination.

Kawai H, Wiederschain D, Yuan ZM. Kawai H, et al. Among authors: yuan zm. Mol Cell Biol. 2003 Jul;23(14):4939-47. doi: 10.1128/MCB.23.14.4939-4947.2003. Mol Cell Biol. 2003. PMID: 12832479 Free PMC article.

4

DNA damage-induced MDMX degradation is mediated by MDM2.

Kawai H, Wiederschain D, Kitao H, Stuart J, Tsai KK, Yuan ZM. Kawai H, et al. Among authors: yuan zm. J Biol Chem. 2003 Nov 14;278(46):45946-53. doi: 10.1074/jbc.M308295200. Epub 2003 Sep 8. J Biol Chem. 2003. PMID: 12963717 Free article.

5

RING domain-mediated interaction is a requirement for MDM2's E3 ligase activity.

Kawai H, Lopez-Pajares V, Kim MM, Wiederschain D, Yuan ZM. Kawai H, et al. Among authors: yuan zm. Cancer Res. 2007 Jul 1;67(13):6026-30. doi: 10.1158/0008-5472.CAN-07-1313. Cancer Res. 2007. PMID: 17616658

6

MDM2 and MDMX: Alone and together in regulation of p53.

Shadfan M, Lopez-Pajares V, Yuan ZM. Shadfan M, et al. Among authors: yuan zm. Transl Cancer Res. 2012 Aug;1(2):88-89. Transl Cancer Res. 2012. PMID: 23002429 Free PMC article.

7

UXT, a novel MDMX-binding protein, promotes glycolysis by mitigating p53-mediated restriction of NF-κB activity.

Qi M, Ganapathy S, Zeng W, Zhang J, Little JB, Yuan ZM. Qi M, et al. Among authors: yuan zm. Oncotarget. 2015 Jul 10;6(19):17584-93. doi: 10.18632/oncotarget.3770. Oncotarget. 2015. PMID: 25974965 Free PMC article.

8

Mutual dependence of MDM2 and MDMX in their functional inactivation of p53.

Gu J, Kawai H, Nie L, Kitao H, Wiederschain D, Jochemsen AG, Parant J, Lozano G, Yuan ZM. Gu J, et al. Among authors: yuan zm. J Biol Chem. 2002 May 31;277(22):19251-4. doi: 10.1074/jbc.C200150200. Epub 2002 Apr 12. J Biol Chem. 2002. PMID: 11953423 Free article.

9

Subcellular distribution of p53 and p73 are differentially regulated by MDM2.

Gu J, Nie L, Kawai H, Yuan ZM. Gu J, et al. Among authors: yuan zm. Cancer Res. 2001 Sep 15;61(18):6703-7. Cancer Res. 2001. PMID: 11559539

10

Multiple mixed lineage leukemia (MLL) fusion proteins suppress p53-mediated response to DNA damage.

Wiederschain D, Kawai H, Shilatifard A, Yuan ZM. Wiederschain D, et al. Among authors: yuan zm. J Biol Chem. 2005 Jul 1;280(26):24315-21. doi: 10.1074/jbc.M412237200. Epub 2005 Apr 25. J Biol Chem. 2005. PMID: 15851483 Free article.

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