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Inhibition of multiple protective signaling pathways and Ad.5/3 delivery enhances mda-7/IL-24 therapy of malignant glioma.
Hamed HA, Yacoub A, Park MA, Eulitt PJ, Dash R, Sarkar D, Dmitriev IP, Lesniak MS, Shah K, Grant S, Curiel DT, Fisher PB, Dent P. Hamed HA, et al. Among authors: dash r. Mol Ther. 2010 Jun;18(6):1130-1142. doi: 10.1038/mt.2010.29. Epub 2010 Feb 23. Mol Ther. 2010. Retraction in: Mol Ther. 2024 Dec 4;32(12):4524. doi: 10.1016/j.ymthe.2024.08.020 PMID: 20179672 Free PMC article. Retracted.
MDA-7/IL-24 as a cancer therapeutic: from bench to bedside.
Dent P, Yacoub A, Hamed HA, Park MA, Dash R, Bhutia SK, Sarkar D, Gupta P, Emdad L, Lebedeva IV, Sauane M, Su ZZ, Rahmani M, Broaddus WC, Young HF, Lesniak M, Grant S, Curiel DT, Fisher PB. Dent P, et al. Among authors: dash r. Anticancer Drugs. 2010 Sep;21(8):725-31. doi: 10.1097/CAD.0b013e32833cfbe1. Anticancer Drugs. 2010. PMID: 20613485 Free PMC article. Review.
The development of MDA-7/IL-24 as a cancer therapeutic.
Dent P, Yacoub A, Hamed HA, Park MA, Dash R, Bhutia SK, Sarkar D, Wang XY, Gupta P, Emdad L, Lebedeva IV, Sauane M, Su ZZ, Rahmani M, Broaddus WC, Young HF, Lesniak MS, Grant S, Curiel DT, Fisher PB. Dent P, et al. Among authors: dash r. Pharmacol Ther. 2010 Nov;128(2):375-84. doi: 10.1016/j.pharmthera.2010.08.001. Epub 2010 Aug 21. Pharmacol Ther. 2010. PMID: 20732354 Free PMC article. Review.
Melanoma differentiation associated gene-7/interleukin-24 potently induces apoptosis in human myeloid leukemia cells through a process regulated by endoplasmic reticulum stress.
Rahmani M, Mayo M, Dash R, Sokhi UK, Dmitriev IP, Sarkar D, Dent P, Curiel DT, Fisher PB, Grant S. Rahmani M, et al. Among authors: dash r. Mol Pharmacol. 2010 Dec;78(6):1096-104. doi: 10.1124/mol.110.068007. Epub 2010 Sep 21. Mol Pharmacol. 2010. PMID: 20858700 Free PMC article.
mda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity.
Dash R, Bhutia SK, Azab B, Su ZZ, Quinn BA, Kegelmen TP, Das SK, Kim K, Lee SG, Park MA, Yacoub A, Rahmani M, Emdad L, Dmitriev IP, Wang XY, Sarkar D, Grant S, Dent P, Curiel DT, Fisher PB. Dash R, et al. Cytokine Growth Factor Rev. 2010 Oct;21(5):381-91. doi: 10.1016/j.cytogfr.2010.08.004. Cytokine Growth Factor Rev. 2010. PMID: 20926331 Free PMC article. Review.
A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels.
Park MA, Hamed HA, Mitchell C, Cruickshanks N, Dash R, Allegood J, Dmitriev IP, Tye G, Ogretmen B, Spiegel S, Yacoub A, Grant S, Curiel DT, Fisher PB, Dent P. Park MA, et al. Among authors: dash r. Mol Pharmacol. 2011 Mar;79(3):368-80. doi: 10.1124/mol.110.069484. Epub 2010 Nov 30. Mol Pharmacol. 2011. PMID: 21119025 Free PMC article.
750 results