Blundell MP - Search Results

1

Correction of murine SCID-X1 by lentiviral gene therapy using a codon-optimized IL2RG gene and minimal pretransplant conditioning.

Huston MW, van Til NP, Visser TP, Arshad S, Brugman MH, Cattoglio C, Nowrouzi A, Li Y, Schambach A, Schmidt M, Baum C, von Kalle C, Mavilio F, Zhang F, Blundell MP, Thrasher AJ, Verstegen MM, Wagemaker G. Huston MW, et al. Among authors: blundell mp. Mol Ther. 2011 Oct;19(10):1867-77. doi: 10.1038/mt.2011.127. Epub 2011 Jul 12. Mol Ther. 2011. PMID: 21750532 Free PMC article.

2

A defined window for efficient gene marking of severe combined immunodeficient-repopulating cells using a gibbon ape leukemia virus-pseudotyped retroviral vector.

Demaison C, Brouns G, Blundell MP, Goldman JP, Levinsky RJ, Grez M, Kinnon C, Thrasher AJ. Demaison C, et al. Among authors: blundell mp. Hum Gene Ther. 2000 Jan 1;11(1):91-100. doi: 10.1089/10430340050016184. Hum Gene Ther. 2000. PMID: 10646642

3

Impaired bone marrow homing of cytokine-activated CD34+ cells in the NOD/SCID model.

Ahmed F, Ings SJ, Pizzey AR, Blundell MP, Thrasher AJ, Ye HT, Fahey A, Linch DC, Yong KL. Ahmed F, et al. Among authors: blundell mp. Blood. 2004 Mar 15;103(6):2079-87. doi: 10.1182/blood-2003-06-1770. Epub 2003 Nov 20. Blood. 2004. PMID: 14630817 Free article.

4

Lentiviral vectors transcriptionally targeted to hematopoietic cells by WASP gene proximal promoter sequences.

Martín F, Toscano MG, Blundell M, Frecha C, Srivastava GK, Santamaría M, Thrasher AJ, Molina IJ. Martín F, et al. Gene Ther. 2005 Apr;12(8):715-23. doi: 10.1038/sj.gt.3302457. Gene Ther. 2005. PMID: 15750617

5

Lentiviral vectors targeting WASp expression to hematopoietic cells, efficiently transduce and correct cells from WAS patients.

Charrier S, Dupré L, Scaramuzza S, Jeanson-Leh L, Blundell MP, Danos O, Cattaneo F, Aiuti A, Eckenberg R, Thrasher AJ, Roncarolo MG, Galy A. Charrier S, et al. Among authors: blundell mp. Gene Ther. 2007 Mar;14(5):415-28. doi: 10.1038/sj.gt.3302863. Epub 2006 Oct 19. Gene Ther. 2007. PMID: 17051251

6

Stable gene transfer to muscle using non-integrating lentiviral vectors.

Apolonia L, Waddington SN, Fernandes C, Ward NJ, Bouma G, Blundell MP, Thrasher AJ, Collins MK, Philpott NJ. Apolonia L, et al. Among authors: blundell mp. Mol Ther. 2007 Nov;15(11):1947-54. doi: 10.1038/sj.mt.6300281. Epub 2007 Aug 14. Mol Ther. 2007. PMID: 17700544 Free article.

7

Cell-specific and efficient expression in mouse and human B cells by a novel hybrid immunoglobulin promoter in a lentiviral vector.

Laurie KL, Blundell MP, Baxendale HE, Howe SJ, Sinclair J, Qasim W, Brunsberg U, Thrasher AJ, Holmdahl R, Gustafsson K. Laurie KL, et al. Among authors: blundell mp. Gene Ther. 2007 Dec;14(23):1623-31. doi: 10.1038/sj.gt.3303021. Epub 2007 Sep 13. Gene Ther. 2007. PMID: 17851547

8

Hematopoietic-specific lentiviral vectors circumvent cellular toxicity due to ectopic expression of Wiskott-Aldrich syndrome protein.

Toscano MG, Frecha C, Benabdellah K, Cobo M, Blundell M, Thrasher AJ, García-Olivares E, Molina IJ, Martin F. Toscano MG, et al. Hum Gene Ther. 2008 Feb;19(2):179-97. doi: 10.1089/hum.2007.098. Hum Gene Ther. 2008. PMID: 18240968

9

Improvement of migratory defects in a murine model of Wiskott-Aldrich syndrome gene therapy.

Blundell MP, Bouma G, Calle Y, Jones GE, Kinnon C, Thrasher AJ. Blundell MP, et al. Mol Ther. 2008 May;16(5):836-44. doi: 10.1038/mt.2008.43. Epub 2008 Mar 18. Mol Ther. 2008. PMID: 18388921 Free article.

10

Nonintegrating lentivector vaccines stimulate prolonged T-cell and antibody responses and are effective in tumor therapy.

Karwacz K, Mukherjee S, Apolonia L, Blundell MP, Bouma G, Escors D, Collins MK, Thrasher AJ. Karwacz K, et al. Among authors: blundell mp. J Virol. 2009 Apr;83(7):3094-103. doi: 10.1128/JVI.02519-08. Epub 2009 Jan 28. J Virol. 2009. PMID: 19176629 Free PMC article.

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