Maignan J - Search Results

1

The relevance of secondary radicals in the mode of action of anthralin.

Lambelet P, Ducret F, Löliger J, Maignan J, Reichert U, Shroot B. Lambelet P, et al. Among authors: maignan j. Free Radic Biol Med. 1990;9(3):183-90. doi: 10.1016/0891-5849(90)90026-f. Free Radic Biol Med. 1990. PMID: 2177025

2

In vitro and in vivo antiinflammatory activities of C10 substituted anthralin derivatives.

Hensby CN, Shroot B, Chatelus A, Cavey D, Allec J, Maignan J. Hensby CN, et al. Among authors: maignan j. Agents Actions. 1987 Aug;21(3-4):247-9. doi: 10.1007/BF01966480. Agents Actions. 1987. PMID: 3687577 No abstract available.

3

Selective high affinity retinoic acid receptor alpha or beta-gamma ligands.

Delescluse C, Cavey MT, Martin B, Bernard BA, Reichert U, Maignan J, Darmon M, Shroot B. Delescluse C, et al. Among authors: maignan j. Mol Pharmacol. 1991 Oct;40(4):556-62. Mol Pharmacol. 1991. PMID: 1656191

4

Identification of synthetic retinoids with selectivity for human nuclear retinoic acid receptor gamma.

Bernard BA, Bernardon JM, Delescluse C, Martin B, Lenoir MC, Maignan J, Charpentier B, Pilgrim WR, Reichert U, Shroot B. Bernard BA, et al. Among authors: maignan j. Biochem Biophys Res Commun. 1992 Jul 31;186(2):977-83. doi: 10.1016/0006-291x(92)90842-9. Biochem Biophys Res Commun. 1992. PMID: 1323296

5

The respecification of limb pattern by new synthetic retinoids and their interaction with cellular retinoic acid-binding protein.

Maden M, Summerbell D, Maignan J, Darmon M, Shroot B. Maden M, et al. Among authors: maignan j. Differentiation. 1991 May;47(1):49-55. doi: 10.1111/j.1432-0436.1991.tb00220.x. Differentiation. 1991. PMID: 1655545

6

6'-substituted naphthalene-2-carboxylic acid analogs, a new class of retinoic acid receptor subtype-specific ligands.

Graupner G, Malle G, Maignan J, Lang G, Pruniéras M, Pfahl M. Graupner G, et al. Among authors: maignan j. Biochem Biophys Res Commun. 1991 Sep 30;179(3):1554-61. doi: 10.1016/0006-291x(91)91750-7. Biochem Biophys Res Commun. 1991. PMID: 1656958

7

Aminoalkoxycarbonyloxymethyl Ether Prodrugs with a pH-Triggered Release Mechanism: A Case Study Improving the Solubility, Bioavailability, and Efficacy of Antimalarial 4(1H)-Quinolones with Single Dose Cures.

Monastyrskyi A, Brockmeyer F, LaCrue AN, Zhao Y, Maher SP, Maignan JR, Padin-Irizarry V, Sakhno YI, Parvatkar PT, Asakawa AH, Huang L, Casandra D, Mashkouri S, Kyle DE, Manetsch R. Monastyrskyi A, et al. Among authors: maignan jr. J Med Chem. 2021 May 27;64(10):6581-6595. doi: 10.1021/acs.jmedchem.0c01104. Epub 2021 May 12. J Med Chem. 2021. PMID: 33979164 Free PMC article.

8

Design and Synthesis of Orally Bioavailable Piperazine Substituted 4(1H)-Quinolones with Potent Antimalarial Activity: Structure-Activity and Structure-Property Relationship Studies.

Neelarapu R, Maignan JR, Lichorowic CL, Monastyrskyi A, Mutka TS, LaCrue AN, Blake LD, Casandra D, Mashkouri S, Burrows JN, Willis PA, Kyle DE, Manetsch R. Neelarapu R, et al. Among authors: maignan jr. J Med Chem. 2018 Feb 22;61(4):1450-1473. doi: 10.1021/acs.jmedchem.7b00738. Epub 2018 Feb 9. J Med Chem. 2018. PMID: 29215279 Free PMC article.

9

ICI 56,780 Optimization: Structure-Activity Relationship Studies of 7-(2-Phenoxyethoxy)-4(1H)-quinolones with Antimalarial Activity.

Maignan JR, Lichorowic CL, Giarrusso J, Blake LD, Casandra D, Mutka TS, LaCrue AN, Burrows JN, Willis PA, Kyle DE, Manetsch R. Maignan JR, et al. J Med Chem. 2016 Jul 28;59(14):6943-60. doi: 10.1021/acs.jmedchem.6b00759. Epub 2016 Jul 12. J Med Chem. 2016. PMID: 27291102 Free PMC article.

10

Orally bioavailable 6-chloro-7-methoxy-4(1H)-quinolones efficacious against multiple stages of Plasmodium.

Cross RM, Flanigan DL, Monastyrskyi A, LaCrue AN, Sáenz FE, Maignan JR, Mutka TS, White KL, Shackleford DM, Bathurst I, Fronczek FR, Wojtas L, Guida WC, Charman SA, Burrows JN, Kyle DE, Manetsch R. Cross RM, et al. Among authors: maignan jr. J Med Chem. 2014 Nov 13;57(21):8860-79. doi: 10.1021/jm500942v. Epub 2014 Oct 22. J Med Chem. 2014. PMID: 25148516 Free PMC article.

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