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Preadipocyte factor-1 levels are higher in women with hypothalamic amenorrhea and are associated with bone mineral content and bone mineral density through a mechanism independent of leptin.
Aronis KN, Kilim H, Chamberland JP, Breggia A, Rosen C, Mantzoros CS. Aronis KN, et al. Among authors: chamberland jp. J Clin Endocrinol Metab. 2011 Oct;96(10):E1634-9. doi: 10.1210/jc.2011-0600. Epub 2011 Jul 27. J Clin Endocrinol Metab. 2011. PMID: 21795455 Free PMC article. Clinical Trial.
Leptin is an effective treatment for hypothalamic amenorrhea.
Chou SH, Chamberland JP, Liu X, Matarese G, Gao C, Stefanakis R, Brinkoetter MT, Gong H, Arampatzi K, Mantzoros CS. Chou SH, et al. Among authors: chamberland jp. Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6585-90. doi: 10.1073/pnas.1015674108. Epub 2011 Apr 4. Proc Natl Acad Sci U S A. 2011. PMID: 21464293 Free PMC article. Clinical Trial.
Short-term walnut consumption increases circulating total adiponectin and apolipoprotein A concentrations, but does not affect markers of inflammation or vascular injury in obese humans with the metabolic syndrome: data from a double-blinded, randomized, placebo-controlled study.
Aronis KN, Vamvini MT, Chamberland JP, Sweeney LL, Brennan AM, Magkos F, Mantzoros CS. Aronis KN, et al. Among authors: chamberland jp. Metabolism. 2012 Apr;61(4):577-82. doi: 10.1016/j.metabol.2011.09.008. Epub 2011 Nov 9. Metabolism. 2012. PMID: 22075273 Free PMC article. Clinical Trial.
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