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Diacylglycerol kinase α mediates 17-β-estradiol-induced proliferation, motility, and anchorage-independent growth of Hec-1A endometrial cancer cell line through the G protein-coupled estrogen receptor GPR30.
Filigheddu N, Sampietro S, Chianale F, Porporato PE, Gaggianesi M, Gregnanin I, Rainero E, Ferrara M, Perego B, Riboni F, Baldanzi G, Graziani A, Surico N. Filigheddu N, et al. Among authors: porporato pe. Cell Signal. 2011 Dec;23(12):1988-96. doi: 10.1016/j.cellsig.2011.07.009. Epub 2011 Jul 22. Cell Signal. 2011. PMID: 21802511
Diacylglycerol kinase-alpha mediates hepatocyte growth factor-induced epithelial cell scatter by regulating Rac activation and membrane ruffling.
Chianale F, Cutrupi S, Rainero E, Baldanzi G, Porporato PE, Traini S, Filigheddu N, Gnocchi VF, Santoro MM, Parolini O, van Blitterswijk WJ, Sinigaglia F, Graziani A. Chianale F, et al. Among authors: porporato pe. Mol Biol Cell. 2007 Dec;18(12):4859-71. doi: 10.1091/mbc.e07-02-0177. Epub 2007 Sep 26. Mol Biol Cell. 2007. PMID: 17898083 Free PMC article.
The diacylglycerol kinase α/atypical PKC/β1 integrin pathway in SDF-1α mammary carcinoma invasiveness.
Rainero E, Cianflone C, Porporato PE, Chianale F, Malacarne V, Bettio V, Ruffo E, Ferrara M, Benecchia F, Capello D, Paster W, Locatelli I, Bertoni A, Filigheddu N, Sinigaglia F, Norman JC, Baldanzi G, Graziani A. Rainero E, et al. Among authors: porporato pe. PLoS One. 2014 Jun 2;9(6):e97144. doi: 10.1371/journal.pone.0097144. eCollection 2014. PLoS One. 2014. PMID: 24887021 Free PMC article.
Ghrelin and des-acyl ghrelin promote differentiation and fusion of C2C12 skeletal muscle cells.
Filigheddu N, Gnocchi VF, Coscia M, Cappelli M, Porporato PE, Taulli R, Traini S, Baldanzi G, Chianale F, Cutrupi S, Arnoletti E, Ghè C, Fubini A, Surico N, Sinigaglia F, Ponzetto C, Muccioli G, Crepaldi T, Graziani A. Filigheddu N, et al. Among authors: porporato pe. Mol Biol Cell. 2007 Mar;18(3):986-94. doi: 10.1091/mbc.e06-05-0402. Epub 2007 Jan 3. Mol Biol Cell. 2007. PMID: 17202410 Free PMC article.
Diacylglycerol kinase alpha mediates HGF-induced Rac activation and membrane ruffling by regulating atypical PKC and RhoGDI.
Chianale F, Rainero E, Cianflone C, Bettio V, Pighini A, Porporato PE, Filigheddu N, Serini G, Sinigaglia F, Baldanzi G, Graziani A. Chianale F, et al. Among authors: porporato pe. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4182-7. doi: 10.1073/pnas.0908326107. Epub 2010 Feb 16. Proc Natl Acad Sci U S A. 2010. PMID: 20160093 Free PMC article.
SAP-mediated inhibition of diacylglycerol kinase α regulates TCR-induced diacylglycerol signaling.
Baldanzi G, Pighini A, Bettio V, Rainero E, Traini S, Chianale F, Porporato PE, Filigheddu N, Mesturini R, Song S, Schweighoffer T, Patrussi L, Baldari CT, Zhong XP, van Blitterswijk WJ, Sinigaglia F, Nichols KE, Rubio I, Parolini O, Graziani A. Baldanzi G, et al. Among authors: porporato pe. J Immunol. 2011 Dec 1;187(11):5941-51. doi: 10.4049/jimmunol.1002476. Epub 2011 Nov 2. J Immunol. 2011. PMID: 22048771 Free PMC article.
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