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Loss-of-function RNAi screens in breast cancer cells identify AURKB, PLK1, PIK3R1, MAPK12, PRKD2, and PTK6 as sensitizing targets of rapamycin activity.
Ou O, Huppi K, Chakka S, Gehlhaus K, Dubois W, Patel J, Chen J, Mackiewicz M, Jones TL, Pitt JJ, Martin SE, Goldsmith P, Simmons JK, Mock BA, Caplen NJ. Ou O, et al. Among authors: pitt jj. Cancer Lett. 2014 Nov 28;354(2):336-47. doi: 10.1016/j.canlet.2014.08.043. Epub 2014 Sep 1. Cancer Lett. 2014. PMID: 25193464 Free PMC article.
Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells.
Hummon AB, Pitt JJ, Camps J, Emons G, Skube SB, Huppi K, Jones TL, Beissbarth T, Kramer F, Grade M, Difilippantonio MJ, Ried T, Caplen NJ. Hummon AB, et al. Among authors: pitt jj. Mol Cancer. 2012 Jan 4;11:1. doi: 10.1186/1476-4598-11-1. Mol Cancer. 2012. PMID: 22216762 Free PMC article.
Genomic instability and mouse microRNAs.
Huppi K, Pitt J, Wahlberg B, Caplen NJ. Huppi K, et al. Toxicol Mech Methods. 2011 May;21(4):325-33. doi: 10.3109/15376516.2011.562759. Toxicol Mech Methods. 2011. PMID: 21495870 Free PMC article. Review.
Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas.
Huo D, Hu H, Rhie SK, Gamazon ER, Cherniack AD, Liu J, Yoshimatsu TF, Pitt JJ, Hoadley KA, Troester M, Ru Y, Lichtenberg T, Sturtz LA, Shelley CS, Benz CC, Mills GB, Laird PW, Shriver CD, Perou CM, Olopade OI. Huo D, et al. Among authors: pitt jj. JAMA Oncol. 2017 Dec 1;3(12):1654-1662. doi: 10.1001/jamaoncol.2017.0595. JAMA Oncol. 2017. PMID: 28472234 Free PMC article.
Immune pathway upregulation and lower genomic instability distinguish EBV-positive nodal T/NK-cell lymphoma from ENKTL and PTCL-NOS.
Wai CMM, Chen S, Phyu T, Fan S, Leong SM, Zheng W, Low LCY, Choo SN, Lee CK, Chung TH, Ban KHK, Ghosh S, Lie S, Kato S, Nakamura S, Takahashi E, Ko YH, Khoury JD, Chuang SS, Au-Yeung RKH, Tan SY, Lim ST, Ong CK, Ho YH, Poon LM, De Mel S, Jeyasekharan AD, Chng WJ, Otto F, Quintanilla-Martinez L, Zanardi F, Iannelli F, Tripodo C, Pitt JJ, Ng SB. Wai CMM, et al. Among authors: pitt jj. Haematologica. 2022 Aug 1;107(8):1864-1879. doi: 10.3324/haematol.2021.280003. Haematologica. 2022. PMID: 35021606 Free PMC article.
75 results