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Activation of tumor-associated macrophages by the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid induces an effective CD8+ T-cell-mediated antitumor immune response in murine models of lung cancer and mesothelioma.
Jassar AS, Suzuki E, Kapoor V, Sun J, Silverberg MB, Cheung L, Burdick MD, Strieter RM, Ching LM, Kaiser LR, Albelda SM. Jassar AS, et al. Among authors: sun j. Cancer Res. 2005 Dec 15;65(24):11752-61. doi: 10.1158/0008-5472.CAN-05-1658. Cancer Res. 2005. PMID: 16357188
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