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Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A.
Jankowska AM, Makishima H, Tiu RV, Szpurka H, Huang Y, Traina F, Visconte V, Sugimoto Y, Prince C, O'Keefe C, Hsi ED, List A, Sekeres MA, Rao A, McDevitt MA, Maciejewski JP. Jankowska AM, et al. Among authors: huang y. Blood. 2011 Oct 6;118(14):3932-41. doi: 10.1182/blood-2010-10-311019. Epub 2011 Aug 9. Blood. 2011. PMID: 21828135 Free PMC article.
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2.
Ko M, Huang Y, Jankowska AM, Pape UJ, Tahiliani M, Bandukwala HS, An J, Lamperti ED, Koh KP, Ganetzky R, Liu XS, Aravind L, Agarwal S, Maciejewski JP, Rao A. Ko M, et al. Among authors: huang y. Nature. 2010 Dec 9;468(7325):839-43. doi: 10.1038/nature09586. Nature. 2010. PMID: 21057493 Free PMC article.
New functions for DNA modifications by TET-JBP.
Huang Y, Rao A. Huang Y, et al. Nat Struct Mol Biol. 2012 Nov;19(11):1061-4. doi: 10.1038/nsmb.2437. Nat Struct Mol Biol. 2012. PMID: 23132381 Free PMC article.
Large conserved domains of low DNA methylation maintained by Dnmt3a.
Jeong M, Sun D, Luo M, Huang Y, Challen GA, Rodriguez B, Zhang X, Chavez L, Wang H, Hannah R, Kim SB, Yang L, Ko M, Chen R, Göttgens B, Lee JS, Gunaratne P, Godley LA, Darlington GJ, Rao A, Li W, Goodell MA. Jeong M, et al. Among authors: huang y. Nat Genet. 2014 Jan;46(1):17-23. doi: 10.1038/ng.2836. Epub 2013 Nov 24. Nat Genet. 2014. PMID: 24270360 Free PMC article.
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