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Novel multitarget ligand ITH33/IQM9.21 provides neuroprotection in in vitro and in vivo models related to brain ischemia.
Lorrio S, Gómez-Rangel V, Negredo P, Egea J, Leon R, Romero A, Dal-Cim T, Villarroya M, Rodriguez-Franco MI, Conde S, Arce MP, Roda JM, García AG, López MG. Lorrio S, et al. Among authors: conde s. Neuropharmacology. 2013 Apr;67:403-11. doi: 10.1016/j.neuropharm.2012.12.001. Epub 2012 Dec 7. Neuropharmacology. 2013. PMID: 23228428
Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia.
Monjas L, Arce MP, León R, Egea J, Pérez C, Villarroya M, López MG, Gil C, Conde S, Rodríguez-Franco MI. Monjas L, et al. Among authors: conde s. Eur J Med Chem. 2017 Apr 21;130:60-72. doi: 10.1016/j.ejmech.2017.02.034. Epub 2017 Feb 22. Eur J Med Chem. 2017. PMID: 28242552
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.
González-Muñoz GC, Arce MP, López B, Pérez C, Romero A, del Barrio L, Martín-de-Saavedra MD, Egea J, León R, Villarroya M, López MG, García AG, Conde S, Rodríguez-Franco MI. González-Muñoz GC, et al. Among authors: conde s. Eur J Med Chem. 2011 Jun;46(6):2224-35. doi: 10.1016/j.ejmech.2011.03.003. Epub 2011 Mar 21. Eur J Med Chem. 2011. PMID: 21420206
Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties.
Fernández-Bachiller MI, Pérez C, González-Muñoz GC, Conde S, López MG, Villarroya M, García AG, Rodríguez-Franco MI. Fernández-Bachiller MI, et al. Among authors: conde s. J Med Chem. 2010 Jul 8;53(13):4927-37. doi: 10.1021/jm100329q. J Med Chem. 2010. PMID: 20545360
257 results