Towne JE - Search Results

1

Interleukin-36-receptor antagonist deficiency and generalized pustular psoriasis.

Marrakchi S, Guigue P, Renshaw BR, Puel A, Pei XY, Fraitag S, Zribi J, Bal E, Cluzeau C, Chrabieh M, Towne JE, Douangpanya J, Pons C, Mansour S, Serre V, Makni H, Mahfoudh N, Fakhfakh F, Bodemer C, Feingold J, Hadj-Rabia S, Favre M, Genin E, Sahbatou M, Munnich A, Casanova JL, Sims JE, Turki H, Bachelez H, Smahi A. Marrakchi S, et al. Among authors: towne je. N Engl J Med. 2011 Aug 18;365(7):620-8. doi: 10.1056/NEJMoa1013068. N Engl J Med. 2011. PMID: 21848462 Free article.

2

IL-36 in psoriasis.

Towne JE, Sims JE. Towne JE, et al. Curr Opin Pharmacol. 2012 Aug;12(4):486-90. doi: 10.1016/j.coph.2012.02.009. Epub 2012 Mar 5. Curr Opin Pharmacol. 2012. PMID: 22398321 Review.

3

Mutation in IL36RN impairs the processing and regulatory function of the interleukin-36-receptor antagonist and is associated with DITRA syndrome.

Bal E, Lim AC, Shen M, Douangpanya J, Madrange M, Gazah R, Tauber M, Beghdadi W, Casanova JL, Bourrat E, Bachelez H, Towne JE, Smahi A. Bal E, et al. Among authors: towne je. Exp Dermatol. 2019 Oct;28(10):1114-1117. doi: 10.1111/exd.13387. Epub 2017 Oct 26. Exp Dermatol. 2019. PMID: 28603914

4

Interleukin-36 (IL-36) ligands require processing for full agonist (IL-36α, IL-36β, and IL-36γ) or antagonist (IL-36Ra) activity.

Towne JE, Renshaw BR, Douangpanya J, Lipsky BP, Shen M, Gabel CA, Sims JE. Towne JE, et al. J Biol Chem. 2011 Dec 9;286(49):42594-42602. doi: 10.1074/jbc.M111.267922. Epub 2011 Sep 29. J Biol Chem. 2011. PMID: 21965679 Free PMC article.

5

11 IL-1 family members in inflammatory skin disease.

Sims J, Towne J, Blumberg H. Sims J, et al. Ernst Schering Res Found Workshop. 2006;(56):187-91. doi: 10.1007/3-540-37673-9_11. Ernst Schering Res Found Workshop. 2006. PMID: 16329652 Review.

6

SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling.

Wald D, Qin J, Zhao Z, Qian Y, Naramura M, Tian L, Towne J, Sims JE, Stark GR, Li X. Wald D, et al. Among authors: towne j. Nat Immunol. 2003 Sep;4(9):920-7. doi: 10.1038/ni968. Epub 2003 Aug 17. Nat Immunol. 2003. PMID: 12925853

7

Interleukin (IL)-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP to activate the pathway leading to NF-kappaB and MAPKs.

Towne JE, Garka KE, Renshaw BR, Virca GD, Sims JE. Towne JE, et al. J Biol Chem. 2004 Apr 2;279(14):13677-88. doi: 10.1074/jbc.M400117200. Epub 2004 Jan 20. J Biol Chem. 2004. PMID: 14734551 Free article.

8

Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation.

Blumberg H, Dinh H, Trueblood ES, Pretorius J, Kugler D, Weng N, Kanaly ST, Towne JE, Willis CR, Kuechle MK, Sims JE, Peschon JJ. Blumberg H, et al. Among authors: towne je. J Exp Med. 2007 Oct 29;204(11):2603-14. doi: 10.1084/jem.20070157. Epub 2007 Oct 1. J Exp Med. 2007. PMID: 17908936 Free PMC article.

9

IL-1RL2 and its ligands contribute to the cytokine network in psoriasis.

Blumberg H, Dinh H, Dean C Jr, Trueblood ES, Bailey K, Shows D, Bhagavathula N, Aslam MN, Varani J, Towne JE, Sims JE. Blumberg H, et al. Among authors: towne je. J Immunol. 2010 Oct 1;185(7):4354-62. doi: 10.4049/jimmunol.1000313. Epub 2010 Sep 10. J Immunol. 2010. PMID: 20833839

10

The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses.

Lowes MA, Russell CB, Martin DA, Towne JE, Krueger JG. Lowes MA, et al. Among authors: towne je. Trends Immunol. 2013 Apr;34(4):174-81. doi: 10.1016/j.it.2012.11.005. Epub 2013 Jan 3. Trends Immunol. 2013. PMID: 23291100 Free PMC article. Review.

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