Modlich U - Search Results

1

Development of novel efficient SIN vectors with improved safety features for Wiskott-Aldrich syndrome stem cell based gene therapy.

Avedillo Díez I, Zychlinski D, Coci EG, Galla M, Modlich U, Dewey RA, Schwarzer A, Maetzig T, Mpofu N, Jaeckel E, Boztug K, Baum C, Klein C, Schambach A. Avedillo Díez I, et al. Among authors: modlich u. Mol Pharm. 2011 Oct 3;8(5):1525-37. doi: 10.1021/mp200132u. Epub 2011 Aug 31. Mol Pharm. 2011. PMID: 21851067

2

Predictable and efficient retroviral gene transfer into murine bone marrow repopulating cells using a defined vector dose.

Li Z, Schwieger M, Lange C, Kraunus J, Sun H, van den Akker E, Modlich U, Serinsöz E, Will E, von Laer D, Stocking C, Fehse B, Schiedlmeier B, Baum C. Li Z, et al. Among authors: modlich u. Exp Hematol. 2003 Dec;31(12):1206-14. doi: 10.1016/j.exphem.2003.08.008. Exp Hematol. 2003. PMID: 14662326 Free article.

3

Self-inactivating retroviral vectors with improved RNA processing.

Kraunus J, Schaumann DH, Meyer J, Modlich U, Fehse B, Brandenburg G, von Laer D, Klump H, Schambach A, Bohne J, Baum C. Kraunus J, et al. Among authors: modlich u. Gene Ther. 2004 Nov;11(21):1568-78. doi: 10.1038/sj.gt.3302309. Gene Ther. 2004. PMID: 15372067

4

Safety and efficacy in retrovirally modified haematopoietic cell therapy.

Li Z, Modlich U, Baum C. Li Z, et al. Among authors: modlich u. Best Pract Res Clin Haematol. 2004 Sep;17(3):493-503. doi: 10.1016/j.beha.2004.05.009. Best Pract Res Clin Haematol. 2004. PMID: 15498719 Review.

5

Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis.

Modlich U, Kustikova OS, Schmidt M, Rudolph C, Meyer J, Li Z, Kamino K, von Neuhoff N, Schlegelberger B, Kuehlcke K, Bunting KD, Schmidt S, Deichmann A, von Kalle C, Fehse B, Baum C. Modlich U, et al. Blood. 2005 Jun 1;105(11):4235-46. doi: 10.1182/blood-2004-11-4535. Epub 2005 Feb 15. Blood. 2005. PMID: 15713797 Free article.

6

Clonal dominance of hematopoietic stem cells triggered by retroviral gene marking.

Kustikova O, Fehse B, Modlich U, Yang M, Düllmann J, Kamino K, von Neuhoff N, Schlegelberger B, Li Z, Baum C. Kustikova O, et al. Among authors: modlich u. Science. 2005 May 20;308(5725):1171-4. doi: 10.1126/science.1105063. Science. 2005. PMID: 15905401

7

Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors.

Baum C, Kustikova O, Modlich U, Li Z, Fehse B. Baum C, et al. Among authors: modlich u. Hum Gene Ther. 2006 Mar;17(3):253-63. doi: 10.1089/hum.2006.17.253. Hum Gene Ther. 2006. PMID: 16544975 Review.

8

Lentiviral vectors pseudotyped with murine ecotropic envelope: increased biosafety and convenience in preclinical research.

Schambach A, Galla M, Modlich U, Will E, Chandra S, Reeves L, Colbert M, Williams DA, von Kalle C, Baum C. Schambach A, et al. Among authors: modlich u. Exp Hematol. 2006 May;34(5):588-92. doi: 10.1016/j.exphem.2006.02.005. Exp Hematol. 2006. PMID: 16647564 Free article.

9

Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity.

Modlich U, Bohne J, Schmidt M, von Kalle C, Knöss S, Schambach A, Baum C. Modlich U, et al. Blood. 2006 Oct 15;108(8):2545-53. doi: 10.1182/blood-2005-08-024976. Epub 2006 Jul 6. Blood. 2006. PMID: 16825499 Free PMC article.

10

Gene therapy: X-SCID transgene leukaemogenicity.

Thrasher AJ, Gaspar HB, Baum C, Modlich U, Schambach A, Candotti F, Otsu M, Sorrentino B, Scobie L, Cameron E, Blyth K, Neil J, Abina SH, Cavazzana-Calvo M, Fischer A. Thrasher AJ, et al. Among authors: modlich u. Nature. 2006 Sep 21;443(7109):E5-6; discussion E6-7. doi: 10.1038/nature05219. Nature. 2006. PMID: 16988659

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