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MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas.
Mäkinen N, Mehine M, Tolvanen J, Kaasinen E, Li Y, Lehtonen HJ, Gentile M, Yan J, Enge M, Taipale M, Aavikko M, Katainen R, Virolainen E, Böhling T, Koski TA, Launonen V, Sjöberg J, Taipale J, Vahteristo P, Aaltonen LA. Mäkinen N, et al. Among authors: aaltonen la. Science. 2011 Oct 14;334(6053):252-5. doi: 10.1126/science.1208930. Epub 2011 Aug 25. Science. 2011. PMID: 21868628
Clues to the pathogenesis of familial colorectal cancer.
Aaltonen LA, Peltomäki P, Leach FS, Sistonen P, Pylkkänen L, Mecklin JP, Järvinen H, Powell SM, Jen J, Hamilton SR, et al. Aaltonen LA, et al. Science. 1993 May 7;260(5109):812-6. doi: 10.1126/science.8484121. Science. 1993. PMID: 8484121
No evidence of microsatellite instability in bone tumours.
Tarkkanen M, Aaltonen LA, Böhling T, Kivioja A, Karaharju E, Elomaa I, Knuutila S. Tarkkanen M, et al. Among authors: aaltonen la. Br J Cancer. 1996 Aug;74(3):453-5. doi: 10.1038/bjc.1996.380. Br J Cancer. 1996. PMID: 8695363 Free PMC article.
No SMAD4 hypermethylation in colorectal cancer.
Roth S, Laiho P, Salovaara R, Launonen V, Aaltonen LA. Roth S, et al. Among authors: aaltonen la. Br J Cancer. 2000 Oct;83(8):1015-9. doi: 10.1054/bjoc.2000.1387. Br J Cancer. 2000. PMID: 10993648 Free PMC article.
Inherited susceptibility to uterine leiomyomas and renal cell cancer.
Launonen V, Vierimaa O, Kiuru M, Isola J, Roth S, Pukkala E, Sistonen P, Herva R, Aaltonen LA. Launonen V, et al. Among authors: aaltonen la. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3387-92. doi: 10.1073/pnas.051633798. Epub 2001 Feb 27. Proc Natl Acad Sci U S A. 2001. PMID: 11248088 Free PMC article.
E-cadherin is not frequently mutated in hereditary gastric cancer.
Avizienyte E, Launonen V, Salovaara R, Kiviluoto T, Aaltonen LA. Avizienyte E, et al. Among authors: aaltonen la. J Med Genet. 2001 Jan;38(1):49-52. doi: 10.1136/jmg.38.1.49. J Med Genet. 2001. PMID: 11332401 Free PMC article. No abstract available.
444 results