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Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice.
Pérez VI, Cortez LA, Lew CM, Rodriguez M, Webb CR, Van Remmen H, Chaudhuri A, Qi W, Lee S, Bokov A, Fok W, Jones D, Richardson A, Yodoi J, Zhang Y, Tominaga K, Hubbard GB, Ikeno Y. Pérez VI, et al. Among authors: chaudhuri a. J Gerontol A Biol Sci Med Sci. 2011 Dec;66(12):1286-99. doi: 10.1093/gerona/glr125. Epub 2011 Aug 26. J Gerontol A Biol Sci Med Sci. 2011. PMID: 21873593 Free PMC article.
Overexpression of Mn superoxide dismutase does not increase life span in mice.
Jang YC, Pérez VI, Song W, Lustgarten MS, Salmon AB, Mele J, Qi W, Liu Y, Liang H, Chaudhuri A, Ikeno Y, Epstein CJ, Van Remmen H, Richardson A. Jang YC, et al. Among authors: chaudhuri a. J Gerontol A Biol Sci Med Sci. 2009 Nov;64(11):1114-25. doi: 10.1093/gerona/glp100. Epub 2009 Jul 24. J Gerontol A Biol Sci Med Sci. 2009. PMID: 19633237 Free PMC article.
Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity.
Zhang Y, Ikeno Y, Qi W, Chaudhuri A, Li Y, Bokov A, Thorpe SR, Baynes JW, Epstein C, Richardson A, Van Remmen H. Zhang Y, et al. Among authors: chaudhuri a. J Gerontol A Biol Sci Med Sci. 2009 Dec;64(12):1212-20. doi: 10.1093/gerona/glp132. Epub 2009 Sep 23. J Gerontol A Biol Sci Med Sci. 2009. PMID: 19776219 Free PMC article.
Caspase-2 deficiency enhances aging-related traits in mice.
Zhang Y, Padalecki SS, Chaudhuri AR, De Waal E, Goins BA, Grubbs B, Ikeno Y, Richardson A, Mundy GR, Herman B. Zhang Y, et al. Among authors: chaudhuri ar. Mech Ageing Dev. 2007 Feb;128(2):213-21. doi: 10.1016/j.mad.2006.11.030. Epub 2006 Dec 22. Mech Ageing Dev. 2007. PMID: 17188333 Free PMC article.
The role of oxidative damage and stress in aging.
Bokov A, Chaudhuri A, Richardson A. Bokov A, et al. Among authors: chaudhuri a. Mech Ageing Dev. 2004 Oct-Nov;125(10-11):811-26. doi: 10.1016/j.mad.2004.07.009. Mech Ageing Dev. 2004. PMID: 15541775 Review.
Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat.
Pérez VI, Buffenstein R, Masamsetti V, Leonard S, Salmon AB, Mele J, Andziak B, Yang T, Edrey Y, Friguet B, Ward W, Richardson A, Chaudhuri A. Pérez VI, et al. Among authors: chaudhuri a. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3059-64. doi: 10.1073/pnas.0809620106. Epub 2009 Feb 17. Proc Natl Acad Sci U S A. 2009. PMID: 19223593 Free PMC article.
Reduced mitochondrial ROS, enhanced antioxidant defense, and distinct age-related changes in oxidative damage in muscles of long-lived Peromyscus leucopus.
Shi Y, Pulliam DA, Liu Y, Hamilton RT, Jernigan AL, Bhattacharya A, Sloane LB, Qi W, Chaudhuri A, Buffenstein R, Ungvari Z, Austad SN, Van Remmen H. Shi Y, et al. Among authors: chaudhuri a. Am J Physiol Regul Integr Comp Physiol. 2013 Mar 1;304(5):R343-55. doi: 10.1152/ajpregu.00139.2012. Epub 2013 Jan 16. Am J Physiol Regul Integr Comp Physiol. 2013. PMID: 23325454 Free PMC article.
1,352 results