Park SO - Search Results

1

TGF-β signaling in endothelial cells, but not neuroepithelial cells, is essential for cerebral vascular development.

Nguyen HL, Lee YJ, Shin J, Lee E, Park SO, McCarty JH, Oh SP. Nguyen HL, et al. Among authors: park so. Lab Invest. 2011 Nov;91(11):1554-63. doi: 10.1038/labinvest.2011.124. Epub 2011 Aug 29. Lab Invest. 2011. PMID: 21876535 Free PMC article.

2

Genetic ablation of the BMPR2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension.

Hong KH, Lee YJ, Lee E, Park SO, Han C, Beppu H, Li E, Raizada MK, Bloch KD, Oh SP. Hong KH, et al. Among authors: park so. Circulation. 2008 Aug 12;118(7):722-30. doi: 10.1161/CIRCULATIONAHA.107.736801. Epub 2008 Jul 28. Circulation. 2008. PMID: 18663089 Free PMC article.

3

Real-time imaging of de novo arteriovenous malformation in a mouse model of hereditary hemorrhagic telangiectasia.

Park SO, Wankhede M, Lee YJ, Choi EJ, Fliess N, Choe SW, Oh SH, Walter G, Raizada MK, Sorg BS, Oh SP. Park SO, et al. J Clin Invest. 2009 Nov;119(11):3487-96. doi: 10.1172/JCI39482. Epub 2009 Oct 1. J Clin Invest. 2009. PMID: 19805914 Free PMC article.

4

ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2.

Park SO, Lee YJ, Seki T, Hong KH, Fliess N, Jiang Z, Park A, Wu X, Kaartinen V, Roman BL, Oh SP. Park SO, et al. Among authors: park a. Blood. 2008 Jan 15;111(2):633-42. doi: 10.1182/blood-2007-08-107359. Epub 2007 Oct 2. Blood. 2008. PMID: 17911384 Free PMC article.

5

Conditional deletion of Jak2 reveals an essential role in hematopoiesis throughout mouse ontogeny: implications for Jak2 inhibition in humans.

Park SO, Wamsley HL, Bae K, Hu Z, Li X, Choe SW, Slayton WB, Oh SP, Wagner KU, Sayeski PP. Park SO, et al. PLoS One. 2013;8(3):e59675. doi: 10.1371/journal.pone.0059675. Epub 2013 Mar 27. PLoS One. 2013. PMID: 23544085 Free PMC article.

6

The small molecule inhibitor G6 significantly reduces bone marrow fibrosis and the mutant burden in a mouse model of Jak2-mediated myelofibrosis.

Kirabo A, Park SO, Wamsley HL, Gali M, Baskin R, Reinhard MK, Zhao ZJ, Bisht KS, Keserű GM, Cogle CR, Sayeski PP. Kirabo A, et al. Among authors: park so. Am J Pathol. 2012 Sep;181(3):858-65. doi: 10.1016/j.ajpath.2012.05.033. Epub 2012 Jul 13. Am J Pathol. 2012. PMID: 22796437 Free PMC article.

7

The Jak2 small molecule inhibitor, G6, reduces the tumorigenic potential of T98G glioblastoma cells in vitro and in vivo.

Baskin R, Park SO, Keserű GM, Bisht KS, Wamsley HL, Sayeski PP. Baskin R, et al. Among authors: park so. PLoS One. 2014 Aug 27;9(8):e105568. doi: 10.1371/journal.pone.0105568. eCollection 2014. PLoS One. 2014. PMID: 25162558 Free PMC article.

8

The Jak2 inhibitor, G6, alleviates Jak2-V617F-mediated myeloproliferative neoplasia by providing significant therapeutic efficacy to the bone marrow.

Kirabo A, Park SO, Majumder A, Gali M, Reinhard MK, Wamsley HL, Zhao ZJ, Cogle CR, Bisht KS, Keserü GM, Sayeski PP. Kirabo A, et al. Among authors: park so. Neoplasia. 2011 Nov;13(11):1058-68. doi: 10.1593/neo.111112. Neoplasia. 2011. PMID: 22131881 Free PMC article.

9

Elevated levels of mast cells are involved in pruritus associated with polycythemia vera in JAK2V617F transgenic mice.

Jin X, Zhao W, Kirabo A, Park SO, Ho WT, Sayeski PP, Zhao ZJ. Jin X, et al. Among authors: park so. J Immunol. 2014 Jul 15;193(2):477-84. doi: 10.4049/jimmunol.1301946. Epub 2014 Jun 11. J Immunol. 2014. PMID: 24920845

10

A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growth.

Majumder A, Magis AT, Park SO, Figueroa NC, Baskin R, Kirabo A, Allan RW, Zhao ZJ, Bisht KS, Keseru GM, Sayeski PP. Majumder A, et al. Among authors: park so. Exp Hematol. 2012 Jan;40(1):22-34. doi: 10.1016/j.exphem.2011.10.003. Epub 2011 Oct 20. Exp Hematol. 2012. PMID: 22019628 Free PMC article.

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