Kiefersauer R - Search Results

1

Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers.

Gerritz SW, Cianci C, Kim S, Pearce BC, Deminie C, Discotto L, McAuliffe B, Minassian BF, Shi S, Zhu S, Zhai W, Pendri A, Li G, Poss MA, Edavettal S, McDonnell PA, Lewis HA, Maskos K, Mörtl M, Kiefersauer R, Steinbacher S, Baldwin ET, Metzler W, Bryson J, Healy MD, Philip T, Zoeckler M, Schartman R, Sinz M, Leyva-Grado VH, Hoffmann HH, Langley DR, Meanwell NA, Krystal M. Gerritz SW, et al. Among authors: kiefersauer r. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15366-71. doi: 10.1073/pnas.1107906108. Epub 2011 Sep 6. Proc Natl Acad Sci U S A. 2011. PMID: 21896751 Free PMC article.

2

Key factors for successful generation of protein-fragment structures requirement on protein, crystals, and technology.

Böttcher J, Jestel A, Kiefersauer R, Krapp S, Nagel S, Steinbacher S, Steuber H. Böttcher J, et al. Among authors: kiefersauer r. Methods Enzymol. 2011;493:61-89. doi: 10.1016/B978-0-12-381274-2.00003-0. Methods Enzymol. 2011. PMID: 21371587

3

The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism.

Engel M, Hoffmann T, Wagner L, Wermann M, Heiser U, Kiefersauer R, Huber R, Bode W, Demuth HU, Brandstetter H. Engel M, et al. Among authors: kiefersauer r. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5063-8. doi: 10.1073/pnas.0230620100. Epub 2003 Apr 10. Proc Natl Acad Sci U S A. 2003. PMID: 12690074 Free PMC article.

4

Crystal structure of the caspase activator human granzyme B, a proteinase highly specific for an Asp-P1 residue.

Estébanez-Perpiña E, Fuentes-Prior P, Belorgey D, Braun M, Kiefersauer R, Maskos K, Huber R, Rubin H, Bode W. Estébanez-Perpiña E, et al. Among authors: kiefersauer r. Biol Chem. 2000 Dec;381(12):1203-14. doi: 10.1515/BC.2000.148. Biol Chem. 2000. PMID: 11209755

5

Novel irreversible covalent BTK inhibitors discovered using DNA-encoded chemistry.

Guilinger JP, Archna A, Augustin M, Bergmann A, Centrella PA, Clark MA, Cuozzo JW, Däther M, Guié MA, Habeshian S, Kiefersauer R, Krapp S, Lammens A, Lercher L, Liu J, Liu Y, Maskos K, Mrosek M, Pflügler K, Siegert M, Thomson HA, Tian X, Zhang Y, Konz Makino DL, Keefe AD. Guilinger JP, et al. Among authors: kiefersauer r. Bioorg Med Chem. 2021 Jul 15;42:116223. doi: 10.1016/j.bmc.2021.116223. Epub 2021 May 19. Bioorg Med Chem. 2021. PMID: 34091303 Free article.

6

Structural and biochemical characterization of the cell fate determining nucleotidyltransferase fold protein MAB21L1.

de Oliveira Mann CC, Kiefersauer R, Witte G, Hopfner KP. de Oliveira Mann CC, et al. Among authors: kiefersauer r. Sci Rep. 2016 Jun 8;6:27498. doi: 10.1038/srep27498. Sci Rep. 2016. PMID: 27271801 Free PMC article.

7

Catalysis at a dinuclear [CuSMo(==O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution.

Dobbek H, Gremer L, Kiefersauer R, Huber R, Meyer O. Dobbek H, et al. Among authors: kiefersauer r. Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):15971-6. doi: 10.1073/pnas.212640899. Proc Natl Acad Sci U S A. 2002. PMID: 12475995 Free PMC article.

8

The crystal structure of the proprotein processing proteinase furin explains its stringent specificity.

Henrich S, Cameron A, Bourenkov GP, Kiefersauer R, Huber R, Lindberg I, Bode W, Than ME. Henrich S, et al. Among authors: kiefersauer r. Nat Struct Biol. 2003 Jul;10(7):520-6. doi: 10.1038/nsb941. Nat Struct Biol. 2003. PMID: 12794637

9

Crystal structure of protoporphyrinogen IX oxidase: a key enzyme in haem and chlorophyll biosynthesis.

Koch M, Breithaupt C, Kiefersauer R, Freigang J, Huber R, Messerschmidt A. Koch M, et al. Among authors: kiefersauer r. EMBO J. 2004 Apr 21;23(8):1720-8. doi: 10.1038/sj.emboj.7600189. Epub 2004 Apr 1. EMBO J. 2004. PMID: 15057273 Free PMC article.

10

Crystal structures of the tricorn interacting factor F3 from Thermoplasma acidophilum, a zinc aminopeptidase in three different conformations.

Kyrieleis OJ, Goettig P, Kiefersauer R, Huber R, Brandstetter H. Kyrieleis OJ, et al. Among authors: kiefersauer r. J Mol Biol. 2005 Jun 17;349(4):787-800. doi: 10.1016/j.jmb.2005.03.070. Epub 2005 Apr 26. J Mol Biol. 2005. PMID: 15893768

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