Wierenga RK - Search Results

1

The characterization and evolutionary relationships of a trypanosomal thiolase.

Mazet M, Harijan RK, Kiema TR, Haapalainen AM, Morand P, Morales J, Bringaud F, Wierenga RK, Michels PA. Mazet M, et al. Among authors: wierenga rk. Int J Parasitol. 2011 Oct;41(12):1273-83. doi: 10.1016/j.ijpara.2011.07.009. Epub 2011 Aug 26. Int J Parasitol. 2011. PMID: 21907205

2

Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase: the importance of potassium and chloride ions for its structure and function.

Haapalainen AM, Meriläinen G, Pirilä PL, Kondo N, Fukao T, Wierenga RK. Haapalainen AM, et al. Among authors: wierenga rk. Biochemistry. 2007 Apr 10;46(14):4305-21. doi: 10.1021/bi6026192. Epub 2007 Mar 20. Biochemistry. 2007. PMID: 17371050

3

Crystal structures of SCP2-thiolases of Trypanosomatidae, human pathogens causing widespread tropical diseases: the importance for catalysis of the cysteine of the unique HDCF loop.

Harijan RK, Kiema TR, Karjalainen MP, Janardan N, Murthy MR, Weiss MS, Michels PA, Wierenga RK. Harijan RK, et al. Among authors: wierenga rk. Biochem J. 2013 Oct 1;455(1):119-30. doi: 10.1042/BJ20130669. Biochem J. 2013. PMID: 23909465

4

Phylogenetic relationships and classification of thiolases and thiolase-like proteins of Mycobacterium tuberculosis and Mycobacterium smegmatis.

Anbazhagan P, Harijan RK, Kiema TR, Janardan N, Murthy MR, Michels PA, Juffer AH, Wierenga RK. Anbazhagan P, et al. Among authors: wierenga rk. Tuberculosis (Edinb). 2014 Jul;94(4):405-12. doi: 10.1016/j.tube.2014.03.003. Epub 2014 Apr 4. Tuberculosis (Edinb). 2014. PMID: 24825023

5

The SCP2-thiolase-like protein (SLP) of Trypanosoma brucei is an enzyme involved in lipid metabolism.

Harijan RK, Mazet M, Kiema TR, Bouyssou G, Alexson SE, Bergmann U, Moreau P, Michels PA, Bringaud F, Wierenga RK. Harijan RK, et al. Among authors: wierenga rk. Proteins. 2016 Aug;84(8):1075-96. doi: 10.1002/prot.25054. Epub 2016 May 9. Proteins. 2016. PMID: 27093562

6

Crystallographic substrate binding studies of Leishmania mexicana SCP2-thiolase (type-2): unique features of oxyanion hole-1.

Harijan RK, Kiema TR, Syed SM, Qadir I, Mazet M, Bringaud F, Michels PAM, Wierenga RK. Harijan RK, et al. Among authors: wierenga rk. Protein Eng Des Sel. 2017 Mar 1;30(3):225-233. doi: 10.1093/protein/gzw080. Protein Eng Des Sel. 2017. PMID: 28062645

7

Characterization of the genes for fructose-bisphosphate aldolase in Trypanosoma brucei.

Marchand M, Poliszczak A, Gibson WC, Wierenga RK, Opperdoes FR, Michels PA. Marchand M, et al. Among authors: wierenga rk. Mol Biochem Parasitol. 1988 May;29(1):65-75. doi: 10.1016/0166-6851(88)90121-1. Mol Biochem Parasitol. 1988. PMID: 3386689

8

The crystal structure of human mitochondrial 3-ketoacyl-CoA thiolase (T1): insight into the reaction mechanism of its thiolase and thioesterase activities.

Kiema TR, Harijan RK, Strozyk M, Fukao T, Alexson SE, Wierenga RK. Kiema TR, et al. Among authors: wierenga rk. Acta Crystallogr D Biol Crystallogr. 2014 Dec 1;70(Pt 12):3212-25. doi: 10.1107/S1399004714023827. Epub 2014 Nov 22. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 25478839

9

Triose-phosphate isomerase of Leishmania mexicana mexicana. Cloning and characterization of the gene, overexpression in Escherichia coli and analysis of the protein.

Kohl L, Callens M, Wierenga RK, Opperdoes FR, Michels PA. Kohl L, et al. Among authors: wierenga rk. Eur J Biochem. 1994 Mar 1;220(2):331-8. doi: 10.1111/j.1432-1033.1994.tb18629.x. Eur J Biochem. 1994. PMID: 8125090 Free article.

10

The thiolase superfamily: condensing enzymes with diverse reaction specificities.

Haapalainen AM, Meriläinen G, Wierenga RK. Haapalainen AM, et al. Among authors: wierenga rk. Trends Biochem Sci. 2006 Jan;31(1):64-71. doi: 10.1016/j.tibs.2005.11.011. Epub 2005 Dec 13. Trends Biochem Sci. 2006. PMID: 16356722 Review.

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