García-Sastre A - Search Results

1

Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor.

Mata MA, Satterly N, Versteeg GA, Frantz D, Wei S, Williams N, Schmolke M, Peña-Llopis S, Brugarolas J, Forst CV, White MA, García-Sastre A, Roth MG, Fontoura BM. Mata MA, et al. Nat Chem Biol. 2011 Sep 11;7(10):712-9. doi: 10.1038/nchembio.645. Nat Chem Biol. 2011. PMID: 21909097 Free PMC article.

2

PB1-F2 expression by the 2009 pandemic H1N1 influenza virus has minimal impact on virulence in animal models.

Hai R, Schmolke M, Varga ZT, Manicassamy B, Wang TT, Belser JA, Pearce MB, García-Sastre A, Tumpey TM, Palese P. Hai R, et al. J Virol. 2010 May;84(9):4442-50. doi: 10.1128/JVI.02717-09. Epub 2010 Feb 24. J Virol. 2010. PMID: 20181699 Free PMC article.

3

Species-specific antagonism of host ISGylation by the influenza B virus NS1 protein.

Versteeg GA, Hale BG, van Boheemen S, Wolff T, Lenschow DJ, García-Sastre A. Versteeg GA, et al. J Virol. 2010 May;84(10):5423-30. doi: 10.1128/JVI.02395-09. Epub 2010 Mar 10. J Virol. 2010. PMID: 20219937 Free PMC article.

4

Inefficient control of host gene expression by the 2009 pandemic H1N1 influenza A virus NS1 protein.

Hale BG, Steel J, Medina RA, Manicassamy B, Ye J, Hickman D, Hai R, Schmolke M, Lowen AC, Perez DR, García-Sastre A. Hale BG, et al. J Virol. 2010 Jul;84(14):6909-22. doi: 10.1128/JVI.00081-10. Epub 2010 May 5. J Virol. 2010. PMID: 20444891 Free PMC article.

5

Evasion of innate and adaptive immune responses by influenza A virus.

Schmolke M, García-Sastre A. Schmolke M, et al. Cell Microbiol. 2010 Jul;12(7):873-80. doi: 10.1111/j.1462-5822.2010.01475.x. Epub 2010 May 6. Cell Microbiol. 2010. PMID: 20482552 Free PMC article. Review.

6

Viral tricks to grid-lock the type I interferon system.

Versteeg GA, García-Sastre A. Versteeg GA, et al. Curr Opin Microbiol. 2010 Aug;13(4):508-16. doi: 10.1016/j.mib.2010.05.009. Epub 2010 Jun 10. Curr Opin Microbiol. 2010. PMID: 20538505 Free PMC article. Review.

7

The influenza virus protein PB1-F2 inhibits the induction of type I interferon at the level of the MAVS adaptor protein.

Varga ZT, Ramos I, Hai R, Schmolke M, García-Sastre A, Fernandez-Sesma A, Palese P. Varga ZT, et al. PLoS Pathog. 2011 Jun;7(6):e1002067. doi: 10.1371/journal.ppat.1002067. Epub 2011 Jun 9. PLoS Pathog. 2011. PMID: 21695240 Free PMC article.

8

Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species.

Schmolke M, Manicassamy B, Pena L, Sutton T, Hai R, Varga ZT, Hale BG, Steel J, Pérez DR, García-Sastre A. Schmolke M, et al. PLoS Pathog. 2011 Aug;7(8):e1002186. doi: 10.1371/journal.ppat.1002186. Epub 2011 Aug 11. PLoS Pathog. 2011. PMID: 21852950 Free PMC article.

9

HERC6 is the main E3 ligase for global ISG15 conjugation in mouse cells.

Oudshoorn D, van Boheemen S, Sánchez-Aparicio MT, Rajsbaum R, García-Sastre A, Versteeg GA. Oudshoorn D, et al. PLoS One. 2012;7(1):e29870. doi: 10.1371/journal.pone.0029870. Epub 2012 Jan 17. PLoS One. 2012. PMID: 22272257 Free PMC article.

10

Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export.

Zhang L, Das P, Schmolke M, Manicassamy B, Wang Y, Deng X, Cai L, Tu BP, Forst CV, Roth MG, Levy DE, García-Sastre A, de Brabander J, Phillips MA, Fontoura BM. Zhang L, et al. J Cell Biol. 2012 Feb 6;196(3):315-26. doi: 10.1083/jcb.201107058. J Cell Biol. 2012. PMID: 22312003 Free PMC article.

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