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Page 1
Glycosphingolipids and insulin resistance.
Aerts JM, Boot RG, van Eijk M, Groener J, Bijl N, Lombardo E, Bietrix FM, Dekker N, Groen AK, Ottenhoff R, van Roomen C, Aten J, Serlie M, Langeveld M, Wennekes T, Overkleeft HS. Aerts JM, et al. Among authors: overkleeft hs. Adv Exp Med Biol. 2011;721:99-119. doi: 10.1007/978-1-4614-0650-1_7. Adv Exp Med Biol. 2011. PMID: 21910085 Review.
Transglycosidase activity of chitotriosidase: improved enzymatic assay for the human macrophage chitinase.
Aguilera B, Ghauharali-van der Vlugt K, Helmond MT, Out JM, Donker-Koopman WE, Groener JE, Boot RG, Renkema GH, van der Marel GA, van Boom JH, Overkleeft HS, Aerts JM. Aguilera B, et al. Among authors: overkleeft hs. J Biol Chem. 2003 Oct 17;278(42):40911-6. doi: 10.1074/jbc.M301804200. Epub 2003 Jul 30. J Biol Chem. 2003. PMID: 12890686 Free article.
Identification of the non-lysosomal glucosylceramidase as beta-glucosidase 2.
Boot RG, Verhoek M, Donker-Koopman W, Strijland A, van Marle J, Overkleeft HS, Wennekes T, Aerts JM. Boot RG, et al. Among authors: overkleeft hs. J Biol Chem. 2007 Jan 12;282(2):1305-12. doi: 10.1074/jbc.M610544200. Epub 2006 Nov 14. J Biol Chem. 2007. PMID: 17105727 Free article.
Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity.
Aerts JM, Ottenhoff R, Powlson AS, Grefhorst A, van Eijk M, Dubbelhuis PF, Aten J, Kuipers F, Serlie MJ, Wennekes T, Sethi JK, O'Rahilly S, Overkleeft HS. Aerts JM, et al. Among authors: overkleeft hs. Diabetes. 2007 May;56(5):1341-9. doi: 10.2337/db06-1619. Epub 2007 Feb 7. Diabetes. 2007. PMID: 17287460 Free PMC article.
Reducing glycosphingolipid content in adipose tissue of obese mice restores insulin sensitivity, adipogenesis and reduces inflammation.
van Eijk M, Aten J, Bijl N, Ottenhoff R, van Roomen CP, Dubbelhuis PF, Seeman I, Ghauharali-van der Vlugt K, Overkleeft HS, Arbeeny C, Groen AK, Aerts JM. van Eijk M, et al. Among authors: overkleeft hs. PLoS One. 2009;4(3):e4723. doi: 10.1371/journal.pone.0004723. Epub 2009 Mar 23. PLoS One. 2009. PMID: 19305508 Free PMC article.
Visualization of Active Glucocerebrosidase in Rodent Brain with High Spatial Resolution following In Situ Labeling with Fluorescent Activity Based Probes.
Herrera Moro Chao D, Kallemeijn WW, Marques AR, Orre M, Ottenhoff R, van Roomen C, Foppen E, Renner MC, Moeton M, van Eijk M, Boot RG, Kamphuis W, Hol EM, Aten J, Overkleeft HS, Kalsbeek A, Aerts JM. Herrera Moro Chao D, et al. Among authors: overkleeft hs. PLoS One. 2015 Sep 29;10(9):e0138107. doi: 10.1371/journal.pone.0138107. eCollection 2015. PLoS One. 2015. PMID: 26418157 Free PMC article.
510 results