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The zymogen of plasmepsin V from Plasmodium falciparum is enzymatically active.
Xiao H, Bryksa BC, Bhaumik P, Gustchina A, Kiso Y, Yao SQ, Wlodawer A, Yada RY. Xiao H, et al. Among authors: kiso y. Mol Biochem Parasitol. 2014 Oct;197(1-2):56-63. doi: 10.1016/j.molbiopara.2014.10.004. Epub 2014 Oct 25. Mol Biochem Parasitol. 2014. PMID: 25447707 Free PMC article.
Structure of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae bound to an allophenylnorstatine-based inhibitor.
Clemente JC, Govindasamy L, Madabushi A, Fisher SZ, Moose RE, Yowell CA, Hidaka K, Kimura T, Hayashi Y, Kiso Y, Agbandje-McKenna M, Dame JB, Dunn BM, McKenna R. Clemente JC, et al. Among authors: kiso y. Acta Crystallogr D Biol Crystallogr. 2006 Mar;62(Pt 3):246-52. doi: 10.1107/S0907444905041260. Epub 2006 Feb 22. Acta Crystallogr D Biol Crystallogr. 2006. PMID: 16510971
575 results