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Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in mice.
Nori S, Okada Y, Yasuda A, Tsuji O, Takahashi Y, Kobayashi Y, Fujiyoshi K, Koike M, Uchiyama Y, Ikeda E, Toyama Y, Yamanaka S, Nakamura M, Okano H. Nori S, et al. Among authors: uchiyama y. Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16825-30. doi: 10.1073/pnas.1108077108. Epub 2011 Sep 26. Proc Natl Acad Sci U S A. 2011. PMID: 21949375 Free PMC article.
Long-term safety issues of iPSC-based cell therapy in a spinal cord injury model: oncogenic transformation with epithelial-mesenchymal transition.
Nori S, Okada Y, Nishimura S, Sasaki T, Itakura G, Kobayashi Y, Renault-Mihara F, Shimizu A, Koya I, Yoshida R, Kudoh J, Koike M, Uchiyama Y, Ikeda E, Toyama Y, Nakamura M, Okano H. Nori S, et al. Among authors: uchiyama y. Stem Cell Reports. 2015 Mar 10;4(3):360-73. doi: 10.1016/j.stemcr.2015.01.006. Epub 2015 Feb 13. Stem Cell Reports. 2015. PMID: 25684226 Free PMC article.
RNA-binding protein Musashi family: roles for CNS stem cells and a subpopulation of ependymal cells revealed by targeted disruption and antisense ablation.
Sakakibara S, Nakamura Y, Yoshida T, Shibata S, Koike M, Takano H, Ueda S, Uchiyama Y, Noda T, Okano H. Sakakibara S, et al. Among authors: uchiyama y. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15194-9. doi: 10.1073/pnas.232087499. Epub 2002 Oct 29. Proc Natl Acad Sci U S A. 2002. PMID: 12407178 Free PMC article.
Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue.
Imaizumi Y, Okada Y, Akamatsu W, Koike M, Kuzumaki N, Hayakawa H, Nihira T, Kobayashi T, Ohyama M, Sato S, Takanashi M, Funayama M, Hirayama A, Soga T, Hishiki T, Suematsu M, Yagi T, Ito D, Kosakai A, Hayashi K, Shouji M, Nakanishi A, Suzuki N, Mizuno Y, Mizushima N, Amagai M, Uchiyama Y, Mochizuki H, Hattori N, Okano H. Imaizumi Y, et al. Among authors: uchiyama y. Mol Brain. 2012 Oct 6;5:35. doi: 10.1186/1756-6606-5-35. Mol Brain. 2012. PMID: 23039195 Free PMC article.
Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes.
Uchida Y, Hasegawa J, Chinnapen D, Inoue T, Okazaki S, Kato R, Wakatsuki S, Misaki R, Koike M, Uchiyama Y, Iemura S, Natsume T, Kuwahara R, Nakagawa T, Nishikawa K, Mukai K, Miyoshi E, Taniguchi N, Sheff D, Lencer WI, Taguchi T, Arai H. Uchida Y, et al. Among authors: uchiyama y. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15846-51. doi: 10.1073/pnas.1109101108. Epub 2011 Sep 12. Proc Natl Acad Sci U S A. 2011. PMID: 21911378 Free PMC article.
Autophagic neuron death.
Uchiyama Y, Koike M, Shibata M, Sasaki M. Uchiyama Y, et al. Methods Enzymol. 2009;453:33-51. doi: 10.1016/S0076-6879(08)04003-2. Methods Enzymol. 2009. PMID: 19216901
1,211 results