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Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells.
Marzec M, Liu X, Wysocka M, Rook AH, Odum N, Wasik MA. Marzec M, et al. PLoS One. 2011;6(9):e24849. doi: 10.1371/journal.pone.0024849. Epub 2011 Sep 16. PLoS One. 2011. Retraction in: PLoS One. 2020 Sep 10;15(9):e0239102. doi: 10.1371/journal.pone.0239102 PMID: 21949767 Free PMC article. Retracted.
Initially usually indolent, CTCL displays a tendency to progress to the aggressive forms with limited response to therapy and poor prognosis. Our previous study (M. Marzec et al. 2008) has demonstrated that CTCL cells display mTORC1 activation and short-term treatme …
Initially usually indolent, CTCL displays a tendency to progress to the aggressive forms with limited response to therapy and poor prognosis …
Activation of mTORC1 signaling pathway in AIDS-related lymphomas.
El-Salem M, Raghunath PN, Marzec M, Liu X, Kasprzycka M, Robertson E, Wasik MA. El-Salem M, et al. Among authors: marzec m. Am J Pathol. 2009 Aug;175(2):817-24. doi: 10.2353/ajpath.2009.080451. Epub 2009 Jul 16. Am J Pathol. 2009. PMID: 19608873 Free PMC article.
Oncogenic kinase NPM/ALK induces expression of HIF1α mRNA.
Marzec M, Liu X, Wong W, Yang Y, Pasha T, Kantekure K, Zhang P, Woetmann A, Cheng M, Odum N, Wasik MA. Marzec M, et al. Oncogene. 2011 Mar 17;30(11):1372-8. doi: 10.1038/onc.2010.505. Epub 2010 Nov 22. Oncogene. 2011. PMID: 21102525
235 results