Hamlin DK - Search Results

1

Pretargeted radioimmunotherapy using genetically engineered antibody-streptavidin fusion proteins for treatment of non-hodgkin lymphoma.

Park SI, Shenoi J, Frayo SM, Hamlin DK, Lin Y, Wilbur DS, Stayton PS, Orgun N, Hylarides M, Buchegger F, Kenoyer AL, Axtman A, Gopal AK, Green DJ, Pagel JM, Press OW. Park SI, et al. Among authors: hamlin dk. Clin Cancer Res. 2011 Dec 1;17(23):7373-82. doi: 10.1158/1078-0432.CCR-11-1204. Epub 2011 Oct 5. Clin Cancer Res. 2011. PMID: 21976541 Free PMC article.

2

Monoclonal antibody Fab' fragment cross-linking using equilibrium transfer alkylation reagents. A strategy for site-specific conjugation of diagnostic and therapeutic agents with F(ab')2 fragments.

Wilbur DS, Stray JE, Hamlin DK, Curtis DK, Vessella RL. Wilbur DS, et al. Among authors: hamlin dk. Bioconjug Chem. 1994 May-Jun;5(3):220-35. doi: 10.1021/bc00027a007. Bioconjug Chem. 1994. PMID: 7918742

3

Antibody fragments in tumor pretargeting. Evaluation of biotinylated Fab' colocalization with recombinant streptavidin and avidin.

Wilbur DS, Hamlin DK, Vessella RL, Stray JE, Buhler KR, Stayton PS, Klumb LA, Pathare PM, Weerawarna SA. Wilbur DS, et al. Among authors: hamlin dk. Bioconjug Chem. 1996 Nov-Dec;7(6):689-702. doi: 10.1021/bc9600628. Bioconjug Chem. 1996. PMID: 8950488

4

Biotin reagents for antibody pretargeting. 2. Synthesis and in vitro evaluation of biotin dimers and trimers for cross-linking of streptavidin.

Wilbur DS, Pathare PM, Hamlin DK, Weerawarna SA. Wilbur DS, et al. Among authors: hamlin dk. Bioconjug Chem. 1997 Nov-Dec;8(6):819-32. doi: 10.1021/bc970053e. Bioconjug Chem. 1997. PMID: 9404654

5

Streptavidin in antibody pretargeting. Comparison of a recombinant streptavidin with two streptavidin mutant proteins and two commercially available streptavidin proteins.

Wilbur DS, Stayton PS, To R, Buhler KR, Klumb LA, Hamlin DK, Stray JE, Vessella RL. Wilbur DS, et al. Among authors: hamlin dk. Bioconjug Chem. 1998 Jan-Feb;9(1):100-7. doi: 10.1021/bc970152s. Bioconjug Chem. 1998. PMID: 9460552

6

Streptavidin in antibody pretargeting. 2. Evaluation Of methods for decreasing localization of streptavidin to kidney while retaining its tumor binding capacity.

Wilbur DS, Hamlin DK, Buhler KR, Pathare PM, Vessella RL, Stayton PS, To R. Wilbur DS, et al. Among authors: hamlin dk. Bioconjug Chem. 1998 May-Jun;9(3):322-30. doi: 10.1021/bc970182v. Bioconjug Chem. 1998. PMID: 9576806

7

Biotin reagents for antibody pretargeting. 3. Synthesis, radioiodination, and evaluation of biotinylated starburst dendrimers.

Wilbur DS, Pathare PM, Hamlin DK, Buhler KR, Vessella RL. Wilbur DS, et al. Among authors: hamlin dk. Bioconjug Chem. 1998 Nov-Dec;9(6):813-25. doi: 10.1021/bc980055e. Bioconjug Chem. 1998. PMID: 9815176

8

Engineering the isoelectric point of a renal cell carcinoma targeting antibody greatly enhances scFv solubility.

Tan PH, Chu V, Stray JE, Hamlin DK, Pettit D, Wilbur DS, Vessella RL, Stayton PS. Tan PH, et al. Among authors: hamlin dk. Immunotechnology. 1998 Oct;4(2):107-14. doi: 10.1016/s1380-2933(98)00011-6. Immunotechnology. 1998. PMID: 9853952

9

Development of new biotin/streptavidin reagents for pretargeting.

Wilbur DS, Pathare PM, Hamlin DK, Stayton PS, To R, Klumb LA, Buhler KR, Vessella RL. Wilbur DS, et al. Among authors: hamlin dk. Biomol Eng. 1999 Dec 31;16(1-4):113-8. doi: 10.1016/s1050-3862(99)00044-3. Biomol Eng. 1999. PMID: 10796993 Review.

10

Biotin reagents for antibody pretargeting. 4. Selection of biotin conjugates for in vivo application based on their dissociation rate from avidin and streptavidin.

Wilbur DS, Chyan MK, Pathare PM, Hamlin DK, Frownfelter MB, Kegley BB. Wilbur DS, et al. Among authors: hamlin dk. Bioconjug Chem. 2000 Jul-Aug;11(4):569-83. doi: 10.1021/bc000024v. Bioconjug Chem. 2000. PMID: 10898580

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