Stevens PD - Search Results

1

PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth.

Liu J, Stevens PD, Li X, Schmidt MD, Gao T. Liu J, et al. Among authors: stevens pd. Mol Cell Biol. 2011 Dec;31(24):4917-27. doi: 10.1128/MCB.05799-11. Epub 2011 Oct 10. Mol Cell Biol. 2011. PMID: 21986499 Free PMC article.

2

The deubiquitination enzyme USP46 functions as a tumor suppressor by controlling PHLPP-dependent attenuation of Akt signaling in colon cancer.

Li X, Stevens PD, Yang H, Gulhati P, Wang W, Evers BM, Gao T. Li X, et al. Among authors: stevens pd. Oncogene. 2013 Jan 24;32(4):471-8. doi: 10.1038/onc.2012.66. Epub 2012 Mar 5. Oncogene. 2013. PMID: 22391563 Free PMC article.

3

mTOR-dependent regulation of PHLPP expression controls the rapamycin sensitivity in cancer cells.

Liu J, Stevens PD, Gao T. Liu J, et al. Among authors: stevens pd. J Biol Chem. 2011 Feb 25;286(8):6510-20. doi: 10.1074/jbc.M110.183087. Epub 2010 Dec 22. J Biol Chem. 2011. PMID: 21177869 Free PMC article.

4

Protein phosphatase PPM1G regulates protein translation and cell growth by dephosphorylating 4E binding protein 1 (4E-BP1).

Liu J, Stevens PD, Eshleman NE, Gao T. Liu J, et al. Among authors: stevens pd. J Biol Chem. 2013 Aug 9;288(32):23225-33. doi: 10.1074/jbc.M113.492371. Epub 2013 Jun 28. J Biol Chem. 2013. PMID: 23814053 Free PMC article.

5

Downregulation of PHLPP expression contributes to hypoxia-induced resistance to chemotherapy in colon cancer cells.

Wen YA, Stevens PD, Gasser ML, Andrei R, Gao T. Wen YA, et al. Among authors: stevens pd. Mol Cell Biol. 2013 Nov;33(22):4594-605. doi: 10.1128/MCB.00695-13. Epub 2013 Sep 23. Mol Cell Biol. 2013. PMID: 24061475 Free PMC article.

6

PHLPP is a negative regulator of RAF1, which reduces colorectal cancer cell motility and prevents tumor progression in mice.

Li X, Stevens PD, Liu J, Yang H, Wang W, Wang C, Zeng Z, Schmidt MD, Yang M, Lee EY, Gao T. Li X, et al. Among authors: stevens pd. Gastroenterology. 2014 May;146(5):1301-12.e1-10. doi: 10.1053/j.gastro.2014.02.003. Epub 2014 Feb 11. Gastroenterology. 2014. PMID: 24530606 Free PMC article.

7

PHLPP negatively regulates cell motility through inhibition of Akt activity and integrin expression in pancreatic cancer cells.

Smith AJ, Wen YA, Stevens PD, Liu J, Wang C, Gao T. Smith AJ, et al. Among authors: stevens pd. Oncotarget. 2016 Feb 16;7(7):7801-15. doi: 10.18632/oncotarget.6848. Oncotarget. 2016. PMID: 26760962 Free PMC article.

8

mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways.

Gulhati P, Bowen KA, Liu J, Stevens PD, Rychahou PG, Chen M, Lee EY, Weiss HL, O'Connor KL, Gao T, Evers BM. Gulhati P, et al. Among authors: stevens pd. Cancer Res. 2011 May 1;71(9):3246-56. doi: 10.1158/0008-5472.CAN-10-4058. Epub 2011 Mar 23. Cancer Res. 2011. PMID: 21430067 Free PMC article.

9

Erbin Suppresses KSR1-Mediated RAS/RAF Signaling and Tumorigenesis in Colorectal Cancer.

Stevens PD, Wen YA, Xiong X, Zaytseva YY, Li AT, Wang C, Stevens AT, Farmer TN, Gan T, Weiss HL, Inagaki M, Marchetto S, Borg JP, Gao T. Stevens PD, et al. Cancer Res. 2018 Sep 1;78(17):4839-4852. doi: 10.1158/0008-5472.CAN-17-3629. Epub 2018 Jul 6. Cancer Res. 2018. PMID: 29980571 Free PMC article.

10

Inhibition of protein tyrosine phosphatase receptor type F suppresses Wnt signaling in colorectal cancer.

Gan T, Stevens AT, Xiong X, Wen YA, Farmer TN, Li AT, Stevens PD, Golshani S, Weiss HL, Evers BM, Gao T. Gan T, et al. Among authors: stevens pd. Oncogene. 2020 Oct;39(44):6789-6801. doi: 10.1038/s41388-020-01472-z. Epub 2020 Sep 24. Oncogene. 2020. PMID: 32973331 Free PMC article.

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