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Page 1
Inducible NOS inhibition reverses tobacco-smoke-induced emphysema and pulmonary hypertension in mice.
Seimetz M, Parajuli N, Pichl A, Veit F, Kwapiszewska G, Weisel FC, Milger K, Egemnazarov B, Turowska A, Fuchs B, Nikam S, Roth M, Sydykov A, Medebach T, Klepetko W, Jaksch P, Dumitrascu R, Garn H, Voswinckel R, Kostin S, Seeger W, Schermuly RT, Grimminger F, Ghofrani HA, Weissmann N. Seimetz M, et al. Among authors: klepetko w. Cell. 2011 Oct 14;147(2):293-305. doi: 10.1016/j.cell.2011.08.035. Cell. 2011. PMID: 22000010 Free article.
Stimulation of soluble guanylate cyclase prevents cigarette smoke-induced pulmonary hypertension and emphysema.
Weissmann N, Lobo B, Pichl A, Parajuli N, Seimetz M, Puig-Pey R, Ferrer E, Peinado VI, Domínguez-Fandos D, Fysikopoulos A, Stasch JP, Ghofrani HA, Coll-Bonfill N, Frey R, Schermuly RT, García-Lucio J, Blanco I, Bednorz M, Tura-Ceide O, Tadele E, Brandes RP, Grimminger J, Klepetko W, Jaksch P, Rodriguez-Roisin R, Seeger W, Grimminger F, Barberà JA. Weissmann N, et al. Among authors: klepetko w. Am J Respir Crit Care Med. 2014 Jun 1;189(11):1359-73. doi: 10.1164/rccm.201311-2037OC. Am J Respir Crit Care Med. 2014. PMID: 24738736
The noncanonical WNT pathway is operative in idiopathic pulmonary arterial hypertension.
Laumanns IP, Fink L, Wilhelm J, Wolff JC, Mitnacht-Kraus R, Graef-Hoechst S, Stein MM, Bohle RM, Klepetko W, Hoda MA, Schermuly RT, Grimminger F, Seeger W, Voswinckel R. Laumanns IP, et al. Among authors: klepetko w. Am J Respir Cell Mol Biol. 2009 Jun;40(6):683-91. doi: 10.1165/rcmb.2008-0153OC. Epub 2008 Nov 21. Am J Respir Cell Mol Biol. 2009. PMID: 19029018
Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension.
Schermuly RT, Stasch JP, Pullamsetti SS, Middendorff R, Müller D, Schlüter KD, Dingendorf A, Hackemack S, Kolosionek E, Kaulen C, Dumitrascu R, Weissmann N, Mittendorf J, Klepetko W, Seeger W, Ghofrani HA, Grimminger F. Schermuly RT, et al. Among authors: klepetko w. Eur Respir J. 2008 Oct;32(4):881-91. doi: 10.1183/09031936.00114407. Epub 2008 Jun 11. Eur Respir J. 2008. PMID: 18550612 Free article.
Impact of S-adenosylmethionine decarboxylase 1 on pulmonary vascular remodeling.
Weisel FC, Kloepping C, Pichl A, Sydykov A, Kojonazarov B, Wilhelm J, Roth M, Ridge KM, Igarashi K, Nishimura K, Maison W, Wackendorff C, Klepetko W, Jaksch P, Ghofrani HA, Grimminger F, Seeger W, Schermuly RT, Weissmann N, Kwapiszewska G. Weisel FC, et al. Among authors: klepetko w. Circulation. 2014 Apr 8;129(14):1510-23. doi: 10.1161/CIRCULATIONAHA.113.006402. Epub 2014 Jan 27. Circulation. 2014. PMID: 24470481
NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD.
Seimetz M, Sommer N, Bednorz M, Pak O, Veith C, Hadzic S, Gredic M, Parajuli N, Kojonazarov B, Kraut S, Wilhelm J, Knoepp F, Henneke I, Pichl A, Kanbagli ZI, Scheibe S, Fysikopoulos A, Wu CY, Klepetko W, Jaksch P, Eichstaedt C, Grünig E, Hinderhofer K, Geiszt M, Müller N, Rezende F, Buchmann G, Wittig I, Hecker M, Hecker A, Padberg W, Dorfmüller P, Gattenlöhner S, Vogelmeier CF, Günther A, Karnati S, Baumgart-Vogt E, Schermuly RT, Ghofrani HA, Seeger W, Schröder K, Grimminger F, Brandes RP, Weissmann N. Seimetz M, et al. Among authors: klepetko w. Nat Metab. 2020 Jun;2(6):532-546. doi: 10.1038/s42255-020-0215-8. Epub 2020 Jun 8. Nat Metab. 2020. PMID: 32694733
638 results