Eng C - Search Results

1

GATA2 negatively regulates PTEN by preventing nuclear translocation of androgen receptor and by androgen-independent suppression of PTEN transcription in breast cancer.

Wang Y, He X, Ngeow J, Eng C. Wang Y, et al. Among authors: eng c. Hum Mol Genet. 2012 Feb 1;21(3):569-76. doi: 10.1093/hmg/ddr491. Epub 2011 Oct 21. Hum Mol Genet. 2012. PMID: 22021428

2

PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies.

Dahia PL, Aguiar RC, Alberta J, Kum JB, Caron S, Sill H, Marsh DJ, Ritz J, Freedman A, Stiles C, Eng C. Dahia PL, et al. Among authors: eng c. Hum Mol Genet. 1999 Feb;8(2):185-93. doi: 10.1093/hmg/8.2.185. Hum Mol Genet. 1999. PMID: 9931326

3

PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome.

Marsh DJ, Kum JB, Lunetta KL, Bennett MJ, Gorlin RJ, Ahmed SF, Bodurtha J, Crowe C, Curtis MA, Dasouki M, Dunn T, Feit H, Geraghty MT, Graham JM Jr, Hodgson SV, Hunter A, Korf BR, Manchester D, Miesfeldt S, Murday VA, Nathanson KL, Parisi M, Pober B, Romano C, Eng C, et al. Marsh DJ, et al. Among authors: eng c. Hum Mol Genet. 1999 Aug;8(8):1461-72. doi: 10.1093/hmg/8.8.1461. Hum Mol Genet. 1999. PMID: 10400993

4

Germline and germline mosaic PTEN mutations associated with a Proteus-like syndrome of hemihypertrophy, lower limb asymmetry, arteriovenous malformations and lipomatosis.

Zhou XP, Marsh DJ, Hampel H, Mulliken JB, Gimm O, Eng C. Zhou XP, et al. Among authors: eng c. Hum Mol Genet. 2000 Mar 22;9(5):765-8. doi: 10.1093/hmg/9.5.765. Hum Mol Genet. 2000. PMID: 10749983

5

PTEN induces apoptosis and cell cycle arrest through phosphoinositol-3-kinase/Akt-dependent and -independent pathways.

Weng L, Brown J, Eng C. Weng L, et al. Among authors: eng c. Hum Mol Genet. 2001 Feb 1;10(3):237-42. doi: 10.1093/hmg/10.3.237. Hum Mol Genet. 2001. PMID: 11159942

6

Transient ectopic expression of PTEN in thyroid cancer cell lines induces cell cycle arrest and cell type-dependent cell death.

Weng LP, Gimm O, Kum JB, Smith WM, Zhou XP, Wynford-Thomas D, Leone G, Eng C. Weng LP, et al. Among authors: eng c. Hum Mol Genet. 2001 Feb 1;10(3):251-8. doi: 10.1093/hmg/10.3.251. Hum Mol Genet. 2001. PMID: 11159944

7

PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model.

Weng LP, Brown JL, Eng C. Weng LP, et al. Among authors: eng c. Hum Mol Genet. 2001 Mar 15;10(6):599-604. doi: 10.1093/hmg/10.6.599. Hum Mol Genet. 2001. PMID: 11230179

8

PTEN inhibits insulin-stimulated MEK/MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1/Grb-2/Sos complex formation in a breast cancer model.

Weng LP, Smith WM, Brown JL, Eng C. Weng LP, et al. Among authors: eng c. Hum Mol Genet. 2001 Mar 15;10(6):605-16. doi: 10.1093/hmg/10.6.605. Hum Mol Genet. 2001. PMID: 11230180

9

Opposite association of two PPARG variants with cancer: overrepresentation of H449H in endometrial carcinoma cases and underrepresentation of P12A in renal cell carcinoma cases.

Smith WM, Zhou XP, Kurose K, Gao X, Latif F, Kroll T, Sugano K, Cannistra SA, Clinton SK, Maher ER, Prior TW, Eng C. Smith WM, et al. Among authors: eng c. Hum Genet. 2001 Aug;109(2):146-51. doi: 10.1007/s004390100563. Hum Genet. 2001. PMID: 11511919

10

Distinct PTEN mutational spectra in hereditary non-polyposis colon cancer syndrome-related endometrial carcinomas compared to sporadic microsatellite unstable tumors.

Zhou XP, Kuismanen S, Nystrom-Lahti M, Peltomaki P, Eng C. Zhou XP, et al. Among authors: eng c. Hum Mol Genet. 2002 Feb 15;11(4):445-50. doi: 10.1093/hmg/11.4.445. Hum Mol Genet. 2002. PMID: 11854177

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