Beekman R - Search Results

1

Retroviral integration mutagenesis in mice and comparative analysis in human AML identify reduced PTP4A3 expression as a prognostic indicator.

Beekman R, Valkhof M, Erkeland SJ, Taskesen E, Rockova V, Peeters JK, Valk PJ, Löwenberg B, Touw IP. Beekman R, et al. PLoS One. 2011;6(10):e26537. doi: 10.1371/journal.pone.0026537. Epub 2011 Oct 20. PLoS One. 2011. PMID: 22028901 Free PMC article.

2

The antioxidant protein peroxiredoxin 4 is epigenetically down regulated in acute promyelocytic leukemia.

Palande KK, Beekman R, van der Meeren LE, Beverloo HB, Valk PJ, Touw IP. Palande KK, et al. Among authors: beekman r. PLoS One. 2011 Jan 20;6(1):e16340. doi: 10.1371/journal.pone.0016340. PLoS One. 2011. PMID: 21283726 Free PMC article.

3

HAT: hypergeometric analysis of tiling-arrays with application to promoter-GeneChip data.

Taskesen E, Beekman R, de Ridder J, Wouters BJ, Peeters JK, Touw IP, Reinders MJ, Delwel R. Taskesen E, et al. Among authors: beekman r. BMC Bioinformatics. 2010 May 21;11:275. doi: 10.1186/1471-2105-11-275. BMC Bioinformatics. 2010. PMID: 20492700 Free PMC article.

4

Sequential gain of mutations in severe congenital neutropenia progressing to acute myeloid leukemia.

Beekman R, Valkhof MG, Sanders MA, van Strien PM, Haanstra JR, Broeders L, Geertsma-Kleinekoort WM, Veerman AJ, Valk PJ, Verhaak RG, Löwenberg B, Touw IP. Beekman R, et al. Blood. 2012 May 31;119(22):5071-7. doi: 10.1182/blood-2012-01-406116. Epub 2012 Feb 27. Blood. 2012. PMID: 22371884 Free article. Clinical Trial.

5

G-CSF and its receptor in myeloid malignancy.

Beekman R, Touw IP. Beekman R, et al. Blood. 2010 Jun 24;115(25):5131-6. doi: 10.1182/blood-2010-01-234120. Epub 2010 Mar 17. Blood. 2010. PMID: 20237318 Free article. Review.

6

Granulocyte colony-stimulating factor receptor signaling: implications for G-CSF responses and leukemic progression in severe congenital neutropenia.

Touw IP, Palande K, Beekman R. Touw IP, et al. Among authors: beekman r. Hematol Oncol Clin North Am. 2013 Feb;27(1):61-73, viii. doi: 10.1016/j.hoc.2012.10.002. Epub 2012 Oct 31. Hematol Oncol Clin North Am. 2013. PMID: 23351988 Review.

7

Prevalence of a new auto-activating colony stimulating factor 3 receptor mutation (CSF3R-T595I) in acute myeloid leukemia and severe congenital neutropenia.

Beekman R, Valkhof M, van Strien P, Valk PJ, Touw IP. Beekman R, et al. Haematologica. 2013 May;98(5):e62-3. doi: 10.3324/haematol.2013.085050. Epub 2013 Mar 18. Haematologica. 2013. PMID: 23508011 Free PMC article. No abstract available.

8

Severe congenital neutropenia and chronic neutrophilic leukemia: an intriguing molecular connection unveiled by oncogenic mutations in CSF3R.

Touw IP, Beekman R. Touw IP, et al. Among authors: beekman r. Haematologica. 2013 Oct;98(10):1490-2. doi: 10.3324/haematol.2013.090571. Haematologica. 2013. PMID: 24091926 Free PMC article. No abstract available.

9

Cooperativity of RUNX1 and CSF3R mutations in severe congenital neutropenia: a unique pathway in myeloid leukemogenesis.

Skokowa J, Steinemann D, Katsman-Kuipers JE, Zeidler C, Klimenkova O, Klimiankou M, Unalan M, Kandabarau S, Makaryan V, Beekman R, Behrens K, Stocking C, Obenauer J, Schnittger S, Kohlmann A, Valkhof MG, Hoogenboezem R, Göhring G, Reinhardt D, Schlegelberger B, Stanulla M, Vandenberghe P, Donadieu J, Zwaan CM, Touw IP, van den Heuvel-Eibrink MM, Dale DC, Welte K. Skokowa J, et al. Among authors: beekman r. Blood. 2014 Apr 3;123(14):2229-37. doi: 10.1182/blood-2013-11-538025. Epub 2014 Feb 12. Blood. 2014. PMID: 24523240 Free article.

10

Myeloid transforming protein Evi1 interacts with methyl-CpG binding domain protein 3 and inhibits in vitro histone deacetylation by Mbd3/Mi-2/NuRD.

Spensberger D, Vermeulen M, Le Guezennec X, Beekman R, van Hoven A, Bindels E, Stunnenberg H, Delwel R. Spensberger D, et al. Among authors: beekman r. Biochemistry. 2008 Jun 17;47(24):6418-26. doi: 10.1021/bi800267f. Epub 2008 May 24. Biochemistry. 2008. PMID: 18500823

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