Valkhof M - Search Results

1

Retroviral integration mutagenesis in mice and comparative analysis in human AML identify reduced PTP4A3 expression as a prognostic indicator.

Beekman R, Valkhof M, Erkeland SJ, Taskesen E, Rockova V, Peeters JK, Valk PJ, Löwenberg B, Touw IP. Beekman R, et al. Among authors: valkhof m. PLoS One. 2011;6(10):e26537. doi: 10.1371/journal.pone.0026537. Epub 2011 Oct 20. PLoS One. 2011. PMID: 22028901 Free PMC article.

2

The gene encoding the transcriptional regulator Yin Yang 1 (YY1) is a myeloid transforming gene interfering with neutrophilic differentiation.

Erkeland SJ, Valkhof M, Heijmans-Antonissen C, Delwel R, Valk PJ, Hermans MH, Touw IP. Erkeland SJ, et al. Among authors: valkhof m. Blood. 2003 Feb 1;101(3):1111-7. doi: 10.1182/blood-2002-04-1207. Epub 2002 Sep 12. Blood. 2003. PMID: 12393438 Free article.

3

Large-scale identification of disease genes involved in acute myeloid leukemia.

Erkeland SJ, Valkhof M, Heijmans-Antonissen C, van Hoven-Beijen A, Delwel R, Hermans MH, Touw IP. Erkeland SJ, et al. Among authors: valkhof m. J Virol. 2004 Feb;78(4):1971-80. doi: 10.1128/jvi.78.4.1971-1980.2004. J Virol. 2004. PMID: 14747562 Free PMC article.

4

The gene encoding thioredoxin-interacting protein (TXNIP) is a frequent virus integration site in virus-induced mouse leukemia and is overexpressed in a subset of AML patients.

Erkeland SJ, Palande KK, Valkhof M, Gits J, Danen-van Oorschot A, Touw IP. Erkeland SJ, et al. Among authors: valkhof m. Leuk Res. 2009 Oct;33(10):1367-71. doi: 10.1016/j.leukres.2009.02.027. Epub 2009 Mar 27. Leuk Res. 2009. PMID: 19327827

5

Sequential gain of mutations in severe congenital neutropenia progressing to acute myeloid leukemia.

Beekman R, Valkhof MG, Sanders MA, van Strien PM, Haanstra JR, Broeders L, Geertsma-Kleinekoort WM, Veerman AJ, Valk PJ, Verhaak RG, Löwenberg B, Touw IP. Beekman R, et al. Among authors: valkhof mg. Blood. 2012 May 31;119(22):5071-7. doi: 10.1182/blood-2012-01-406116. Epub 2012 Feb 27. Blood. 2012. PMID: 22371884 Free article. Clinical Trial.

6

Novel role of WD40 and SOCS box protein-2 in steady-state distribution of granulocyte colony-stimulating factor receptor and G-CSF-controlled proliferation and differentiation signaling.

Erkeland SJ, Aarts LH, Irandoust M, Roovers O, Klomp A, Valkhof M, Gits J, Eyckerman S, Tavernier J, Touw IP. Erkeland SJ, et al. Among authors: valkhof m. Oncogene. 2007 Mar 29;26(14):1985-94. doi: 10.1038/sj.onc.1210004. Epub 2006 Sep 25. Oncogene. 2007. PMID: 17001306

7

A functional single-nucleotide polymorphism of the G-CSF receptor gene predisposes individuals to high-risk myelodysplastic syndrome.

Wölfler A, Erkeland SJ, Bodner C, Valkhof M, Renner W, Leitner C, Olipitz W, Pfeilstöcker M, Tinchon C, Emberger W, Linkesch W, Touw IP, Sill H. Wölfler A, et al. Among authors: valkhof m. Blood. 2005 May 1;105(9):3731-6. doi: 10.1182/blood-2004-06-2094. Epub 2005 Jan 11. Blood. 2005. PMID: 15644419 Free article.

8

Lineage-instructive function of C/EBPα in multipotent hematopoietic cells and early thymic progenitors.

Wölfler A, Danen-van Oorschot AA, Haanstra JR, Valkhof M, Bodner C, Vroegindeweij E, van Strien P, Novak A, Cupedo T, Touw IP. Wölfler A, et al. Among authors: valkhof m. Blood. 2010 Nov 18;116(20):4116-25. doi: 10.1182/blood-2010-03-275404. Epub 2010 Aug 31. Blood. 2010. PMID: 20807890 Free article.

9

Deficiency of the ribosome biogenesis gene Sbds in hematopoietic stem and progenitor cells causes neutropenia in mice by attenuating lineage progression in myelocytes.

Zambetti NA, Bindels EM, Van Strien PM, Valkhof MG, Adisty MN, Hoogenboezem RM, Sanders MA, Rommens JM, Touw IP, Raaijmakers MH. Zambetti NA, et al. Among authors: valkhof mg. Haematologica. 2015 Oct;100(10):1285-93. doi: 10.3324/haematol.2015.131573. Epub 2015 Jul 16. Haematologica. 2015. PMID: 26185170 Free PMC article.

10

Janus kinases promote cell-surface expression and provoke autonomous signalling from routing-defective G-CSF receptors.

Meenhuis A, Irandoust M, Wölfler A, Roovers O, Valkhof M, Touw IP. Meenhuis A, et al. Among authors: valkhof m. Biochem J. 2009 Feb 1;417(3):737-46. doi: 10.1042/BJ20081153. Biochem J. 2009. PMID: 18922133

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