Manallack DT - Search Results

1

Thiophene inhibitors of PDE4: crystal structures show a second binding mode at the catalytic domain of PDE4D2.

Nankervis JL, Feil SC, Hancock NC, Zheng Z, Ng HL, Morton CJ, Holien JK, Ho PW, Frazzetto MM, Jennings IG, Manallack DT, Martin TJ, Thompson PE, Parker MW. Nankervis JL, et al. Among authors: manallack dt. Bioorg Med Chem Lett. 2011 Dec 1;21(23):7089-93. doi: 10.1016/j.bmcl.2011.09.109. Epub 2011 Oct 5. Bioorg Med Chem Lett. 2011. PMID: 22030030

2

The next generation of phosphodiesterase inhibitors: structural clues to ligand and substrate selectivity of phosphodiesterases.

Manallack DT, Hughes RA, Thompson PE. Manallack DT, et al. J Med Chem. 2005 May 19;48(10):3449-62. doi: 10.1021/jm040217u. J Med Chem. 2005. PMID: 15887951 Review. No abstract available.

3

Howard BL, Thompson PE, Manallack DT. Howard BL, et al. Among authors: manallack dt. J Comput Aided Mol Des. 2011 Aug;25(8):753-62. doi: 10.1007/s10822-011-9458-5. Epub 2011 Jul 16. J Comput Aided Mol Des. 2011. PMID: 21766240

4

Structure-activity relationship exploration of Kv1.3 blockers based on diphenoxylate.

Nguyen W, Howard BL, Jenkins DP, Wulff H, Thompson PE, Manallack DT. Nguyen W, et al. Among authors: manallack dt. Bioorg Med Chem Lett. 2012 Dec 1;22(23):7106-9. doi: 10.1016/j.bmcl.2012.09.080. Epub 2012 Sep 29. Bioorg Med Chem Lett. 2012. PMID: 23084278 Free PMC article.

5

Identification of potent phosphodiesterase inhibitors that demonstrate cyclic nucleotide-dependent functions in apicomplexan parasites.

Howard BL, Harvey KL, Stewart RJ, Azevedo MF, Crabb BS, Jennings IG, Sanders PR, Manallack DT, Thompson PE, Tonkin CJ, Gilson PR. Howard BL, et al. Among authors: manallack dt. ACS Chem Biol. 2015 Apr 17;10(4):1145-54. doi: 10.1021/cb501004q. Epub 2015 Feb 4. ACS Chem Biol. 2015. PMID: 25555060

6

Use of Kv1.3 blockers for inflammatory skin conditions.

Nguyen W, Howard BL, Neale DS, Thompson PE, White PJ, Wulff H, Manallack DT. Nguyen W, et al. Among authors: manallack dt. Curr Med Chem. 2010;17(26):2882-96. doi: 10.2174/092986710792065072. Curr Med Chem. 2010. PMID: 20858170 Free PMC article. Review.

7

Synthesis and evaluation of dithiolethiones as novel cyclooxygenase inhibitors.

Zanatta SD, Manallack DT, Jarrott B, Williams SJ. Zanatta SD, et al. Among authors: manallack dt. Bioorg Med Chem Lett. 2009 Jan 15;19(2):459-61. doi: 10.1016/j.bmcl.2008.11.045. Epub 2008 Nov 18. Bioorg Med Chem Lett. 2009. PMID: 19056264

8

The use of tripeptides for lead discovery of 5-HT4 receptor ligands.

Hanna-Elias A, Thompson PE, Manallack DT, Irving HR, Coupar IM, Berque-Bestel I, Iskander MN. Hanna-Elias A, et al. Among authors: manallack dt. Protein Pept Lett. 2009;16(7):805-9. doi: 10.2174/092986609788681805. Protein Pept Lett. 2009. PMID: 19601910

9

Conformational studies on (+)-anatoxin-a and derivatives.

Thompson PE, Manallack DT, Blaney FE, Gallagher T. Thompson PE, et al. Among authors: manallack dt. J Comput Aided Mol Des. 1992 Jun;6(3):287-98. doi: 10.1007/BF00123382. J Comput Aided Mol Des. 1992. PMID: 1517779

10

Synthesis and preliminary screening of novel indole-3-methanamines as 5-HT4 receptor ligands.

Hanna-Elias A, Manallack DT, Berque-Bestel I, Irving HR, Coupar IM, Iskander MN. Hanna-Elias A, et al. Among authors: manallack dt. Eur J Med Chem. 2009 Jul;44(7):2952-9. doi: 10.1016/j.ejmech.2009.01.015. Epub 2009 Jan 24. Eur J Med Chem. 2009. PMID: 19223092

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