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Targeting senescent cholangiocytes and activated fibroblasts with B-cell lymphoma-extra large inhibitors ameliorates fibrosis in multidrug resistance 2 gene knockout (Mdr2-/- ) mice.
Moncsek A, Al-Suraih MS, Trussoni CE, O'Hara SP, Splinter PL, Zuber C, Patsenker E, Valli PV, Fingas CD, Weber A, Zhu Y, Tchkonia T, Kirkland JL, Gores GJ, Müllhaupt B, LaRusso NF, Mertens JC. Moncsek A, et al. Among authors: mertens jc. Hepatology. 2018 Jan;67(1):247-259. doi: 10.1002/hep.29464. Epub 2017 Nov 29. Hepatology. 2018. PMID: 28802066 Free PMC article.
Targeting cholangiocarcinoma.
Mertens JC, Ilyas SI, Gores GJ. Mertens JC, et al. Biochim Biophys Acta Mol Basis Dis. 2018 Apr;1864(4 Pt B):1454-1460. doi: 10.1016/j.bbadis.2017.08.027. Epub 2017 Aug 24. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 28844952 Free PMC article. Review.
Targeting PDGFR-β in Cholangiocarcinoma.
Fingas CD, Mertens JC, Razumilava N, Bronk SF, Sirica AE, Gores GJ. Fingas CD, et al. Among authors: mertens jc. Liver Int. 2012 Mar;32(3):400-9. doi: 10.1111/j.1478-3231.2011.02687.x. Epub 2011 Dec 2. Liver Int. 2012. PMID: 22133064 Free PMC article.
A hedgehog survival pathway in 'undead' lipotoxic hepatocytes.
Kakisaka K, Cazanave SC, Werneburg NW, Razumilava N, Mertens JC, Bronk SF, Gores GJ. Kakisaka K, et al. Among authors: mertens jc. J Hepatol. 2012 Oct;57(4):844-51. doi: 10.1016/j.jhep.2012.05.011. Epub 2012 May 26. J Hepatol. 2012. PMID: 22641094 Free PMC article.
Platelet-derived growth factor-D enables liver myofibroblasts to promote tumor lymphangiogenesis in cholangiocarcinoma.
Cadamuro M, Brivio S, Mertens J, Vismara M, Moncsek A, Milani C, Fingas C, Cristina Malerba M, Nardo G, Dall'Olmo L, Milani E, Mariotti V, Stecca T, Massani M, Spirli C, Fiorotto R, Indraccolo S, Strazzabosco M, Fabris L. Cadamuro M, et al. J Hepatol. 2019 Apr;70(4):700-709. doi: 10.1016/j.jhep.2018.12.004. Epub 2018 Dec 14. J Hepatol. 2019. PMID: 30553841 Free PMC article.
87 results