Hashimoto K - Search Results

1

Human chondrocyte cultures as models of cartilage-specific gene regulation.

Otero M, Favero M, Dragomir C, Hachem KE, Hashimoto K, Plumb DA, Goldring MB. Otero M, et al. Among authors: hashimoto k. Methods Mol Biol. 2012;806:301-36. doi: 10.1007/978-1-61779-367-7_21. Methods Mol Biol. 2012. PMID: 22057461

2

DNA demethylation at specific CpG sites in the IL1B promoter in response to inflammatory cytokines in human articular chondrocytes.

Hashimoto K, Oreffo RO, Gibson MB, Goldring MB, Roach HI. Hashimoto K, et al. Arthritis Rheum. 2009 Nov;60(11):3303-13. doi: 10.1002/art.24882. Arthritis Rheum. 2009. PMID: 19877066 Free PMC article.

3

The epigenetic effect of glucosamine and a nuclear factor-kappa B (NF-kB) inhibitor on primary human chondrocytes--implications for osteoarthritis.

Imagawa K, de Andrés MC, Hashimoto K, Pitt D, Itoi E, Goldring MB, Roach HI, Oreffo RO. Imagawa K, et al. Among authors: hashimoto k. Biochem Biophys Res Commun. 2011 Feb 18;405(3):362-7. doi: 10.1016/j.bbrc.2011.01.007. Epub 2011 Jan 8. Biochem Biophys Res Commun. 2011. PMID: 21219853 Free PMC article.

4

Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis.

Goldring MB, Otero M, Plumb DA, Dragomir C, Favero M, El Hachem K, Hashimoto K, Roach HI, Olivotto E, Borzì RM, Marcu KB. Goldring MB, et al. Among authors: hashimoto k. Eur Cell Mater. 2011 Feb 24;21:202-20. doi: 10.22203/ecm.v021a16. Eur Cell Mater. 2011. PMID: 21351054 Free PMC article.

5

Suppressors of cytokine signalling (SOCS) are reduced in osteoarthritis.

de Andrés MC, Imagawa K, Hashimoto K, Gonzalez A, Goldring MB, Roach HI, Oreffo RO. de Andrés MC, et al. Among authors: hashimoto k. Biochem Biophys Res Commun. 2011 Apr 1;407(1):54-9. doi: 10.1016/j.bbrc.2011.02.101. Epub 2011 Feb 23. Biochem Biophys Res Commun. 2011. PMID: 21352802 Free PMC article.

6

E74-like factor 3 (ELF3) impacts on matrix metalloproteinase 13 (MMP13) transcriptional control in articular chondrocytes under proinflammatory stress.

Otero M, Plumb DA, Tsuchimochi K, Dragomir CL, Hashimoto K, Peng H, Olivotto E, Bevilacqua M, Tan L, Yang Z, Zhan Y, Oettgen P, Li Y, Marcu KB, Goldring MB. Otero M, et al. Among authors: hashimoto k. J Biol Chem. 2012 Jan 27;287(5):3559-72. doi: 10.1074/jbc.M111.265744. Epub 2011 Dec 9. J Biol Chem. 2012. PMID: 22158614 Free PMC article.

7

Loss of methylation in CpG sites in the NF-κB enhancer elements of inducible nitric oxide synthase is responsible for gene induction in human articular chondrocytes.

de Andrés MC, Imagawa K, Hashimoto K, Gonzalez A, Roach HI, Goldring MB, Oreffo RO. de Andrés MC, et al. Among authors: hashimoto k. Arthritis Rheum. 2013 Mar;65(3):732-42. doi: 10.1002/art.37806. Arthritis Rheum. 2013. PMID: 23239081 Free PMC article.

8

Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1β (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites.

Hashimoto K, Otero M, Imagawa K, de Andrés MC, Coico JM, Roach HI, Oreffo ROC, Marcu KB, Goldring MB. Hashimoto K, et al. J Biol Chem. 2013 Apr 5;288(14):10061-10072. doi: 10.1074/jbc.M112.421156. Epub 2013 Feb 15. J Biol Chem. 2013. PMID: 23417678 Free PMC article.

9

Association of reduced type IX collagen gene expression in human osteoarthritic chondrocytes with epigenetic silencing by DNA hypermethylation.

Imagawa K, de Andrés MC, Hashimoto K, Itoi E, Otero M, Roach HI, Goldring MB, Oreffo RO. Imagawa K, et al. Among authors: hashimoto k. Arthritis Rheumatol. 2014 Nov;66(11):3040-51. doi: 10.1002/art.38774. Arthritis Rheumatol. 2014. PMID: 25048791 Free PMC article.

10

ELF3 modulates type II collagen gene (COL2A1) transcription in chondrocytes by inhibiting SOX9-CBP/p300-driven histone acetyltransferase activity.

Otero M, Peng H, Hachem KE, Culley KL, Wondimu EB, Quinn J, Asahara H, Tsuchimochi K, Hashimoto K, Goldring MB. Otero M, et al. Among authors: hashimoto k. Connect Tissue Res. 2017 Jan;58(1):15-26. doi: 10.1080/03008207.2016.1200566. Epub 2016 Jun 16. Connect Tissue Res. 2017. PMID: 27310669 Free PMC article.

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