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Page 1
Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML.
Winter GE, Rix U, Carlson SM, Gleixner KV, Grebien F, Gridling M, Müller AC, Breitwieser FP, Bilban M, Colinge J, Valent P, Bennett KL, White FM, Superti-Furga G. Winter GE, et al. Among authors: gridling m. Nat Chem Biol. 2012 Nov;8(11):905-912. doi: 10.1038/nchembio.1085. Epub 2012 Sep 30. Nat Chem Biol. 2012. PMID: 23023260 Free PMC article.
A target-disease network model of second-generation BCR-ABL inhibitor action in Ph+ ALL.
Rix U, Colinge J, Blatt K, Gridling M, Remsing Rix LL, Parapatics K, Cerny-Reiterer S, Burkard TR, Jäger U, Melo JV, Bennett KL, Valent P, Superti-Furga G. Rix U, et al. Among authors: gridling m. PLoS One. 2013 Oct 10;8(10):e77155. doi: 10.1371/journal.pone.0077155. eCollection 2013. PLoS One. 2013. PMID: 24130846 Free PMC article.
Target interaction profiling of midostaurin and its metabolites in neoplastic mast cells predicts distinct effects on activation and growth.
Peter B, Winter GE, Blatt K, Bennett KL, Stefanzl G, Rix U, Eisenwort G, Hadzijusufovic E, Gridling M, Dutreix C, Hoermann G, Schwaab J, Radia D, Roesel J, Manley PW, Reiter A, Superti-Furga G, Valent P. Peter B, et al. Among authors: gridling m. Leukemia. 2016 Feb;30(2):464-72. doi: 10.1038/leu.2015.242. Epub 2015 Sep 9. Leukemia. 2016. PMID: 26349526 Free PMC article.
Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action.
Babak MV, Meier SM, Huber KVM, Reynisson J, Legin AA, Jakupec MA, Roller A, Stukalov A, Gridling M, Bennett KL, Colinge J, Berger W, Dyson PJ, Superti-Furga G, Keppler BK, Hartinger CG. Babak MV, et al. Among authors: gridling m. Chem Sci. 2015 Apr 1;6(4):2449-2456. doi: 10.1039/c4sc03905j. Epub 2015 Feb 9. Chem Sci. 2015. PMID: 29308157 Free PMC article.
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy.
Huber KV, Salah E, Radic B, Gridling M, Elkins JM, Stukalov A, Jemth AS, Göktürk C, Sanjiv K, Strömberg K, Pham T, Berglund UW, Colinge J, Bennett KL, Loizou JI, Helleday T, Knapp S, Superti-Furga G. Huber KV, et al. Among authors: gridling m. Nature. 2014 Apr 10;508(7495):222-7. doi: 10.1038/nature13194. Epub 2014 Apr 2. Nature. 2014. PMID: 24695225 Free PMC article.
A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis.
Fauster A, Rebsamen M, Huber KV, Bigenzahn JW, Stukalov A, Lardeau CH, Scorzoni S, Bruckner M, Gridling M, Parapatics K, Colinge J, Bennett KL, Kubicek S, Krautwald S, Linkermann A, Superti-Furga G. Fauster A, et al. Among authors: gridling m. Cell Death Dis. 2015 May 21;6(5):e1767. doi: 10.1038/cddis.2015.130. Cell Death Dis. 2015. PMID: 25996294 Free PMC article.
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