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Viral adaptation to host immune responses occurs in chronic hepatitis B virus (HBV) infection, and adaptation is greatest in HBV e antigen-negative disease.
Desmond CP, Gaudieri S, James IR, Pfafferott K, Chopra A, Lau GK, Audsley J, Day C, Chivers S, Gordon A, Revill PA, Bowden S, Ayres A, Desmond PV, Thompson AJ, Roberts SK, Locarnini SA, Mallal SA, Lewin SR. Desmond CP, et al. Among authors: locarnini sa. J Virol. 2012 Jan;86(2):1181-92. doi: 10.1128/JVI.05308-11. Epub 2011 Nov 9. J Virol. 2012. PMID: 22072755 Free PMC article.
Restoration of replication phenotype of lamivudine-resistant hepatitis B virus mutants by compensatory changes in the "fingers" subdomain of the viral polymerase selected as a consequence of mutations in the overlapping S gene.
Torresi J, Earnest-Silveira L, Civitico G, Walters TE, Lewin SR, Fyfe J, Locarnini SA, Manns M, Trautwein C, Bock TC. Torresi J, et al. Among authors: locarnini sa. Virology. 2002 Jul 20;299(1):88-99. doi: 10.1006/viro.2002.1448. Virology. 2002. PMID: 12167344 Free article.
Emerging therapies of hepatitis B and C.
Chen RY, Desmond PV, Locarnini SA. Chen RY, et al. Among authors: locarnini sa. J Gastroenterol Hepatol. 2002 Dec;17 Suppl:S471-81. doi: 10.1046/j.1440-1746.17.s4.13.x. J Gastroenterol Hepatol. 2002. PMID: 12534781 Review. No abstract available.
158 results