Keppler B - Search Results

1

Gallium compound GaQ(3) -induced Ca(2+) signalling triggers p53-dependent and -independent apoptosis in cancer cells.

Gogna R, Madan E, Keppler B, Pati U. Gogna R, et al. Among authors: keppler b. Br J Pharmacol. 2012 May;166(2):617-36. doi: 10.1111/j.1476-5381.2011.01780.x. Br J Pharmacol. 2012. PMID: 22074401 Free PMC article.

2

p53 increases intra-cellular calcium release by transcriptional regulation of calcium channel TRPC6 in GaQ3-treated cancer cells.

Madan E, Gogna R, Keppler B, Pati U. Madan E, et al. Among authors: keppler b. PLoS One. 2013 Aug 16;8(8):e71016. doi: 10.1371/journal.pone.0071016. eCollection 2013. PLoS One. 2013. PMID: 23976973 Free PMC article.

3

Anticancer activity of the lanthanum compound [tris(1,10-phenanthroline)lanthanum(III)]trithiocyanate (KP772; FFC24).

Heffeter P, Jakupec MA, Körner W, Wild S, von Keyserlingk NG, Elbling L, Zorbas H, Korynevska A, Knasmüller S, Sutterlüty H, Micksche M, Keppler BK, Berger W. Heffeter P, et al. Biochem Pharmacol. 2006 Feb 14;71(4):426-40. doi: 10.1016/j.bcp.2005.11.009. Epub 2005 Dec 15. Biochem Pharmacol. 2006. PMID: 16343446

4

The gallium complex KP46 exerts strong activity against primary explanted melanoma cells and induces apoptosis in melanoma cell lines.

Valiahdi SM, Heffeter P, Jakupec MA, Marculescu R, Berger W, Rappersberger K, Keppler BK. Valiahdi SM, et al. Melanoma Res. 2009 Oct;19(5):283-93. doi: 10.1097/CMR.0b013e32832b272d. Melanoma Res. 2009. PMID: 19584767 Free PMC article.

5

Calpain-mediated integrin deregulation as a novel mode of action for the anticancer gallium compound KP46.

Jungwirth U, Gojo J, Tuder T, Walko G, Holcmann M, Schöfl T, Nowikovsky K, Wilfinger N, Schoonhoven S, Kowol CR, Lemmens-Gruber R, Heffeter P, Keppler BK, Berger W. Jungwirth U, et al. Mol Cancer Ther. 2014 Oct;13(10):2436-49. doi: 10.1158/1535-7163.MCT-14-0087. Epub 2014 Jul 31. Mol Cancer Ther. 2014. PMID: 25082959

6

Gallium in cancer treatment.

Jakupec MA, Keppler BK. Jakupec MA, et al. Curr Top Med Chem. 2004;4(15):1575-83. doi: 10.2174/1568026043387449. Curr Top Med Chem. 2004. PMID: 15579097 Review.

7

Anticancer activity of methyl-substituted oxaliplatin analogs.

Jungwirth U, Xanthos DN, Gojo J, Bytzek AK, Körner W, Heffeter P, Abramkin SA, Jakupec MA, Hartinger CG, Windberger U, Galanski M, Keppler BK, Berger W. Jungwirth U, et al. Mol Pharmacol. 2012 May;81(5):719-28. doi: 10.1124/mol.111.077321. Epub 2012 Feb 13. Mol Pharmacol. 2012. PMID: 22331606 Free PMC article.

8

Novel p53-dependent anticancer strategy by targeting iron signaling and BNIP3L-induced mitophagy.

Wilfinger N, Austin S, Scheiber-Mojdehkar B, Berger W, Reipert S, Praschberger M, Paur J, Trondl R, Keppler BK, Zielinski CC, Nowikovsky K. Wilfinger N, et al. Among authors: keppler bk. Oncotarget. 2016 Jan 12;7(2):1242-61. doi: 10.18632/oncotarget.6233. Oncotarget. 2016. PMID: 26517689 Free PMC article.

9

Distinct activity of the bone-targeted gallium compound KP46 against osteosarcoma cells - synergism with autophagy inhibition.

Kubista B, Schoefl T, Mayr L, van Schoonhoven S, Heffeter P, Windhager R, Keppler BK, Berger W. Kubista B, et al. Among authors: keppler bk. J Exp Clin Cancer Res. 2017 Apr 12;36(1):52. doi: 10.1186/s13046-017-0527-z. J Exp Clin Cancer Res. 2017. PMID: 28403890 Free PMC article.

10

Multidrug-resistant cancer cells are preferential targets of the new antineoplastic lanthanum compound KP772 (FFC24).

Heffeter P, Jakupec MA, Körner W, Chiba P, Pirker C, Dornetshuber R, Elbling L, Sutterlüty H, Micksche M, Keppler BK, Berger W. Heffeter P, et al. Among authors: keppler bk. Biochem Pharmacol. 2007 Jun 15;73(12):1873-86. doi: 10.1016/j.bcp.2007.03.002. Epub 2007 Mar 12. Biochem Pharmacol. 2007. PMID: 17445775 Free PMC article.

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