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A subset of chronic lymphocytic leukemia patients display reduced levels of PARP1 expression coupled with a defective irradiation-induced apoptosis.
Bacalini MG, Tavolaro S, Peragine N, Marinelli M, Santangelo S, Del Giudice I, Mauro FR, Di Maio V, Ricciardi MR, Caiafa P, Chiaretti S, Foà R, Guarini A, Reale A. Bacalini MG, et al. Among authors: marinelli m. Exp Hematol. 2012 Mar;40(3):197-206.e1. doi: 10.1016/j.exphem.2011.11.005. Epub 2011 Nov 23. Exp Hematol. 2012. PMID: 22120020 Free article.
Genetic landscape of ultra-stable chronic lymphocytic leukemia patients.
Raponi S, Del Giudice I, Marinelli M, Wang J, Cafforio L, Ilari C, Piciocchi A, Messina M, Bonina S, Tavolaro S, Bordyuh M, Mariglia P, Peragine N, Mauro FR, Chiaretti S, Molica S, Gentile M, Visentin A, Trentin L, Rigolin GM, Cuneo A, Diop F, Rossi D, Gaidano G, Guarini A, Rabadan R, Foà R. Raponi S, et al. Among authors: marinelli m. Ann Oncol. 2018 Apr 1;29(4):966-972. doi: 10.1093/annonc/mdy021. Ann Oncol. 2018. PMID: 29365086 Free PMC article.
BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgV H unmutated chronic lymphocytic leukemia (CLL) cells.
Guarini A, Chiaretti S, Tavolaro S, Maggio R, Peragine N, Citarella F, Ricciardi MR, Santangelo S, Marinelli M, De Propris MS, Messina M, Mauro FR, Del Giudice I, Foà R. Guarini A, et al. Among authors: marinelli m. Blood. 2008 Aug 1;112(3):782-92. doi: 10.1182/blood-2007-12-127688. Epub 2008 May 16. Blood. 2008. PMID: 18487510 Free article.
Gene expression profile of protein kinases reveals a distinctive signature in chronic lymphocytic leukemia and in vitro experiments support a role of second generation protein kinase inhibitors.
Tavolaro S, Chiaretti S, Messina M, Peragine N, Del Giudice I, Marinelli M, Santangelo S, Mauro FR, Guarini A, Foà R. Tavolaro S, et al. Among authors: marinelli m. Leuk Res. 2010 Jun;34(6):733-41. doi: 10.1016/j.leukres.2009.11.005. Epub 2009 Dec 24. Leuk Res. 2010. PMID: 20036005
White blood cell count at diagnosis and immunoglobulin variable region gene mutations are independent predictors of treatment-free survival in young patients with stage A chronic lymphocytic leukemia.
Del Giudice I, Mauro FR, De Propris MS, Santangelo S, Marinelli M, Peragine N, Di Maio V, Nanni M, Barzotti R, Mancini F, Armiento D, Paoloni F, Guarini A, Foà R. Del Giudice I, et al. Among authors: marinelli m. Haematologica. 2011 Apr;96(4):626-30. doi: 10.3324/haematol.2010.028779. Epub 2010 Dec 29. Haematologica. 2011. PMID: 21193417 Free PMC article.
Evaluation of TP53 mutations with the AmpliChip p53 research test in chronic lymphocytic leukemia: correlation with clinical outcome and gene expression profiling.
Chiaretti S, Tavolaro S, Marinelli M, Messina M, Del Giudice I, Mauro FR, Santangelo S, Piciocchi A, Peragine N, Truong S, Patten N, Ghia EM, Torrente I, De Propris MS, Nanni M, Lawrence J, Guarini A, Foà R. Chiaretti S, et al. Among authors: marinelli m. Genes Chromosomes Cancer. 2011 Apr;50(4):263-74. doi: 10.1002/gcc.20852. Epub 2011 Jan 13. Genes Chromosomes Cancer. 2011. PMID: 21319261
ATM gene alterations in chronic lymphocytic leukemia patients induce a distinct gene expression profile and predict disease progression.
Guarini A, Marinelli M, Tavolaro S, Bellacchio E, Magliozzi M, Chiaretti S, De Propris MS, Peragine N, Santangelo S, Paoloni F, Nanni M, Del Giudice I, Mauro FR, Torrente I, Foà R. Guarini A, et al. Among authors: marinelli m. Haematologica. 2012 Jan;97(1):47-55. doi: 10.3324/haematol.2011.049270. Epub 2011 Oct 11. Haematologica. 2012. PMID: 21993670 Free PMC article.
NOTCH1 mutations in +12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of +12 CLL.
Del Giudice I, Rossi D, Chiaretti S, Marinelli M, Tavolaro S, Gabrielli S, Laurenti L, Marasca R, Rasi S, Fangazio M, Guarini A, Gaidano G, Foà R. Del Giudice I, et al. Among authors: marinelli m. Haematologica. 2012 Mar;97(3):437-41. doi: 10.3324/haematol.2011.060129. Epub 2011 Dec 29. Haematologica. 2012. PMID: 22207691 Free PMC article.
473 results