Layton G - Search Results

1

Pharmacokinetic effects of coadministration of lersivirine with raltegravir or maraviroc in healthy subjects.

Vourvahis M, Langdon G, Labadie RR, Layton G, Ndongo MN, Banerjee S, Davis J. Vourvahis M, et al. Among authors: layton g. Antimicrob Agents Chemother. 2012 Feb;56(2):887-92. doi: 10.1128/AAC.00572-11. Epub 2011 Nov 28. Antimicrob Agents Chemother. 2012. PMID: 22123705 Free PMC article. Clinical Trial.

2

Effects of ketoconazole and valproic acid on the pharmacokinetics of the next generation NNRTI, lersivirine (UK-453,061), in healthy adult subjects.

Langdon G, Davis J, Layton G, Chong CL, Weissgerber G, Vourvahis M. Langdon G, et al. Among authors: layton g. Br J Clin Pharmacol. 2012 May;73(5):768-75. doi: 10.1111/j.1365-2125.2011.04136.x. Br J Clin Pharmacol. 2012. PMID: 22040521 Free PMC article. Clinical Trial.

3

The pharmacokinetics of lersivirine (UK-453,061) and HIV-1 protease inhibitor coadministration in healthy subjects.

Vourvahis M, Langdon G, Layton G, Labadie RR, Choo HW, Ndongo MN, Davis J. Vourvahis M, et al. Among authors: layton g. J Acquir Immune Defic Syndr. 2012 May 1;60(1):24-32. doi: 10.1097/QAI.0b013e31824c4186. J Acquir Immune Defic Syndr. 2012. PMID: 22517413 Clinical Trial.

4

The effect of lersivirine, a next-generation NNRTI, on the pharmacokinetics of midazolam and oral contraceptives in healthy subjects.

Davis J, Langdon G, Layton G, Chong CL, Ndongo MN, Vourvahis M. Davis J, et al. Among authors: layton g. Eur J Clin Pharmacol. 2012 Nov;68(11):1567-72. doi: 10.1007/s00228-012-1287-5. Epub 2012 Apr 22. Eur J Clin Pharmacol. 2012. PMID: 22527351 Clinical Trial.

5

Effect of rifampin and rifabutin on the pharmacokinetics of lersivirine and effect of lersivirine on the pharmacokinetics of rifabutin and 25-O-desacetyl-rifabutin in healthy subjects.

Vourvahis M, Davis J, Wang R, Layton G, Choo HW, Chong CL, Tawadrous M. Vourvahis M, et al. Among authors: layton g. Antimicrob Agents Chemother. 2012 Aug;56(8):4303-9. doi: 10.1128/AAC.06282-11. Epub 2012 May 29. Antimicrob Agents Chemother. 2012. PMID: 22644026 Free PMC article. Clinical Trial.

6

Pharmacokinetic interactions between lersivirine and zidovudine, tenofovir disoproxil fumarate/emtricitabine and abacavir/lamivudine.

Vourvahis M, Davis J, Langdon G, Layton G, Fang J, Choo HW, Hansson AG, Tawadrous M. Vourvahis M, et al. Among authors: layton g. Antivir Ther. 2013;18(6):745-54. doi: 10.3851/IMP2566. Epub 2013 Apr 4. Antivir Ther. 2013. PMID: 23558061 Clinical Trial.

7

Effect of single doses of maraviroc on the QT/QTc interval in healthy subjects.

Davis JD, Hackman F, Layton G, Higgins T, Sudworth D, Weissgerber G. Davis JD, et al. Among authors: layton g. Br J Clin Pharmacol. 2008 Apr;65 Suppl 1(Suppl 1):68-75. doi: 10.1111/j.1365-2125.2008.03138.x. Br J Clin Pharmacol. 2008. PMID: 18333868 Free PMC article. Clinical Trial.

8

Activity, pharmacokinetics and safety of lersivirine (UK-453,061), a next-generation nonnucleoside reverse transcriptase inhibitor, during 7-day monotherapy in HIV-1-infected patients.

Fätkenheuer G, Staszewski S, Plettenburg A, Hackman F, Layton G, McFadyen L, Davis J, Jenkins TM. Fätkenheuer G, et al. Among authors: layton g. AIDS. 2009 Oct 23;23(16):2115-22. doi: 10.1097/QAD.0b013e32832fef5b. AIDS. 2009. PMID: 19779321 Clinical Trial.

9

No clinically significant effect of erythromycin or azithromycin on the pharmacokinetics of voriconazole in healthy male volunteers.

Purkins L, Wood N, Ghahramani P, Kleinermans D, Layton G, Nichols D. Purkins L, et al. Among authors: layton g. Br J Clin Pharmacol. 2003 Dec;56 Suppl 1(Suppl 1):30-6. doi: 10.1046/j.1365-2125.2003.01996.x. Br J Clin Pharmacol. 2003. PMID: 14616411 Free PMC article. Clinical Trial.

10

Effect of omeprazole on the steady-state pharmacokinetics of voriconazole.

Wood N, Tan K, Purkins L, Layton G, Hamlin J, Kleinermans D, Nichols D. Wood N, et al. Among authors: layton g. Br J Clin Pharmacol. 2003 Dec;56 Suppl 1(Suppl 1):56-61. doi: 10.1046/j.1365-2125.2003.02000.x. Br J Clin Pharmacol. 2003. PMID: 14616415 Free PMC article. Clinical Trial.

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