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Mice with cardiac overexpression of peroxisome proliferator-activated receptor γ have impaired repolarization and spontaneous fatal ventricular arrhythmias.
Morrow JP, Katchman A, Son NH, Trent CM, Khan R, Shiomi T, Huang H, Amin V, Lader JM, Vasquez C, Morley GE, D'Armiento J, Homma S, Goldberg IJ, Marx SO. Morrow JP, et al. Among authors: homma s. Circulation. 2011 Dec 20;124(25):2812-21. doi: 10.1161/CIRCULATIONAHA.111.056309. Epub 2011 Nov 28. Circulation. 2011. PMID: 22124376 Free PMC article.
Cardiomyocyte expression of PPARgamma leads to cardiac dysfunction in mice.
Son NH, Park TS, Yamashita H, Yokoyama M, Huggins LA, Okajima K, Homma S, Szabolcs MJ, Huang LS, Goldberg IJ. Son NH, et al. Among authors: homma s. J Clin Invest. 2007 Oct;117(10):2791-801. doi: 10.1172/JCI30335. J Clin Invest. 2007. PMID: 17823655 Free PMC article.
Inhibition of c-Jun-N-terminal kinase increases cardiac peroxisome proliferator-activated receptor alpha expression and fatty acid oxidation and prevents lipopolysaccharide-induced heart dysfunction.
Drosatos K, Drosatos-Tampakaki Z, Khan R, Homma S, Schulze PC, Zannis VI, Goldberg IJ. Drosatos K, et al. Among authors: homma s. J Biol Chem. 2011 Oct 21;286(42):36331-9. doi: 10.1074/jbc.M111.272146. Epub 2011 Aug 26. J Biol Chem. 2011. PMID: 21873422 Free PMC article.
1,381 results