Kettschau G - Search Results

1

In vivo evaluation in cynomolgus monkey brain and metabolism of [¹⁸F]fluorodeprenyl: a new MAO-B pet radioligand.

Nag S, Varrone A, Tóth M, Thiele A, Kettschau G, Heinrich T, Lehmann L, Halldin C. Nag S, et al. Among authors: kettschau g. Synapse. 2012 Apr;66(4):323-30. doi: 10.1002/syn.21514. Epub 2011 Dec 30. Synapse. 2012. PMID: 22124971

2

Synthesis and evaluation of [¹⁸F]fluororasagiline, a novel positron emission tomography (PET) radioligand for monoamine oxidase B (MAO-B).

Nag S, Lehmann L, Kettschau G, Heinrich T, Thiele A, Varrone A, Gulyas B, Halldin C. Nag S, et al. Among authors: kettschau g. Bioorg Med Chem. 2012 May 1;20(9):3065-71. doi: 10.1016/j.bmc.2012.02.056. Epub 2012 Mar 3. Bioorg Med Chem. 2012. PMID: 22436387

3

Synthesis and biological evaluation of novel propargyl amines as potential fluorine-18 labeled radioligands for detection of MAO-B activity.

Nag S, Kettschau G, Heinrich T, Varrone A, Lehmann L, Gulyas B, Thiele A, Keller É, Halldin C. Nag S, et al. Among authors: kettschau g. Bioorg Med Chem. 2013 Jan 1;21(1):186-95. doi: 10.1016/j.bmc.2012.10.050. Epub 2012 Nov 15. Bioorg Med Chem. 2013. PMID: 23211968

4

Development of a novel fluorine-18 labeled deuterated fluororasagiline ([(18)F]fluororasagiline-D2) radioligand for PET studies of monoamino oxidase B (MAO-B).

Nag S, Lehmann L, Kettschau G, Toth M, Heinrich T, Thiele A, Varrone A, Halldin C. Nag S, et al. Among authors: kettschau g. Bioorg Med Chem. 2013 Nov 1;21(21):6634-41. doi: 10.1016/j.bmc.2013.08.019. Epub 2013 Aug 15. Bioorg Med Chem. 2013. PMID: 24012376

5

Synthesis of three novel fluorine-18 labeled analogues of L-deprenyl for positron emission tomography (PET) studies of monoamine oxidase B (MAO-B).

Nag S, Lehmann L, Heinrich T, Thiele A, Kettschau G, Nakao R, Gulyás B, Halldin C. Nag S, et al. Among authors: kettschau g. J Med Chem. 2011 Oct 27;54(20):7023-9. doi: 10.1021/jm200710b. Epub 2011 Sep 29. J Med Chem. 2011. PMID: 21923198

6

In Vivo and In Vitro Characterization of a Novel MAO-B Inhibitor Radioligand, 18F-Labeled Deuterated Fluorodeprenyl.

Nag S, Fazio P, Lehmann L, Kettschau G, Heinrich T, Thiele A, Svedberg M, Amini N, Leesch S, Catafau AM, Hannestad J, Varrone A, Halldin C. Nag S, et al. Among authors: kettschau g. J Nucl Med. 2016 Feb;57(2):315-20. doi: 10.2967/jnumed.115.161083. Epub 2015 Nov 19. J Nucl Med. 2016. PMID: 26585057 Free article.

7

Preclinical evaluation of BAY 1075553, a novel (18)F-labelled inhibitor of prostate-specific membrane antigen for PET imaging of prostate cancer.

Lesche R, Kettschau G, Gromov AV, Böhnke N, Borkowski S, Mönning U, Hegele-Hartung C, Döhr O, Dinkelborg LM, Graham K. Lesche R, et al. Among authors: kettschau g. Eur J Nucl Med Mol Imaging. 2014 Jan;41(1):89-101. doi: 10.1007/s00259-013-2527-3. Epub 2013 Aug 17. Eur J Nucl Med Mol Imaging. 2014. PMID: 23955632

8

Radiofluorinated derivatives of 2-(phosphonomethyl)pentanedioic acid as inhibitors of prostate specific membrane antigen (PSMA) for the imaging of prostate cancer.

Graham K, Lesche R, Gromov AV, Böhnke N, Schäfer M, Hassfeld J, Dinkelborg L, Kettschau G. Graham K, et al. Among authors: kettschau g. J Med Chem. 2012 Nov 26;55(22):9510-20. doi: 10.1021/jm300710j. Epub 2012 Oct 24. J Med Chem. 2012. PMID: 23025786

9

Discovery and synthesis of (S)-3-[2-(3,4-dimethoxyphenyl)ethoxy]-2- (4,6-dimethylpyrimidin-2-yloxy)-3,3-diphenylpropionic acid (LU 302872), a novel orally active mixed ET(A)/ET(B) receptor antagonist.

Amberg W, Hergenröder S, Hillen H, Jansen R, Kettschau G, Kling A, Klinge D, Raschack M, Riechers H, Unger L. Amberg W, et al. Among authors: kettschau g. J Med Chem. 1999 Aug 12;42(16):3026-32. doi: 10.1021/jm9910425. J Med Chem. 1999. PMID: 10447946

10

Solid-phase synthesis of endothelin receptor antagonists.

Lange UE, Braje WM, Amberg W, Kettschau G. Lange UE, et al. Among authors: kettschau g. Bioorg Med Chem Lett. 2003 May 19;13(10):1721-4. doi: 10.1016/s0960-894x(03)00236-1. Bioorg Med Chem Lett. 2003. PMID: 12729650

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