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Inhibition of activator protein 1 signaling abrogates transforming growth factor β-mediated activation of fibroblasts and prevents experimental fibrosis.
Avouac J, Palumbo K, Tomcik M, Zerr P, Dees C, Horn A, Maurer B, Akhmetshina A, Beyer C, Sadowski A, Schneider H, Shiozawa S, Distler O, Schett G, Allanore Y, Distler JH. Avouac J, et al. Among authors: horn a. Arthritis Rheum. 2012 May;64(5):1642-52. doi: 10.1002/art.33501. Arthritis Rheum. 2012. PMID: 22139817 Free article.
Platelet-derived serotonin links vascular disease and tissue fibrosis.
Dees C, Akhmetshina A, Zerr P, Reich N, Palumbo K, Horn A, Jüngel A, Beyer C, Krönke G, Zwerina J, Reiter R, Alenina N, Maroteaux L, Gay S, Schett G, Distler O, Distler JH. Dees C, et al. Among authors: horn a. J Exp Med. 2011 May 9;208(5):961-72. doi: 10.1084/jem.20101629. Epub 2011 Apr 25. J Exp Med. 2011. PMID: 21518801 Free PMC article.
Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis.
Akhmetshina A, Palumbo K, Dees C, Bergmann C, Venalis P, Zerr P, Horn A, Kireva T, Beyer C, Zwerina J, Schneider H, Sadowski A, Riener MO, MacDougald OA, Distler O, Schett G, Distler JH. Akhmetshina A, et al. Among authors: horn a. Nat Commun. 2012 Mar 13;3:735. doi: 10.1038/ncomms1734. Nat Commun. 2012. PMID: 22415826 Free PMC article.
1,217 results