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Preclinical testing of tandutinib in a transgenic medulloblastoma mouse model.
Ohshima-Hosoyama S, Davare MA, Prajapati SI, Abraham J, Lal S, Nelon LD, Kilcoyne A, Giles FJ, Hanes MA, Rubin BP, Keller C. Ohshima-Hosoyama S, et al. Among authors: abraham j. J Pediatr Hematol Oncol. 2012 Mar;34(2):116-21. doi: 10.1097/MPH.0b013e3182309fe4. J Pediatr Hematol Oncol. 2012. PMID: 22146535 Free PMC article.
Evasion mechanisms to Igf1r inhibition in rhabdomyosarcoma.
Abraham J, Prajapati SI, Nishijo K, Schaffer BS, Taniguchi E, Kilcoyne A, McCleish AT, Nelon LD, Giles FG, Efstratiadis A, LeGallo RD, Nowak BM, Rubin BP, Malempati S, Keller C. Abraham J, et al. Mol Cancer Ther. 2011 Apr;10(4):697-707. doi: 10.1158/1535-7163.MCT-10-0695. Epub 2011 Mar 29. Mol Cancer Ther. 2011. PMID: 21447712 Free PMC article.
IL-4R drives dedifferentiation, mitogenesis, and metastasis in rhabdomyosarcoma.
Hosoyama T, Aslam MI, Abraham J, Prajapati SI, Nishijo K, Michalek JE, Zarzabal LA, Nelon LD, Guttridge DC, Rubin BP, Keller C. Hosoyama T, et al. Among authors: abraham j. Clin Cancer Res. 2011 May 1;17(9):2757-66. doi: 10.1158/1078-0432.CCR-10-3445. Clin Cancer Res. 2011. PMID: 21536546 Free PMC article.
An adaptive Src-PDGFRA-Raf axis in rhabdomyosarcoma.
Abraham J, Chua YX, Glover JM, Tyner JW, Loriaux MM, Kilcoyne A, Giles FJ, Nelon LD, Carew JS, Ouyang Y, Michalek JE, Pal R, Druker BJ, Rubin BP, Keller C. Abraham J, et al. Biochem Biophys Res Commun. 2012 Sep 28;426(3):363-8. doi: 10.1016/j.bbrc.2012.08.092. Epub 2012 Aug 30. Biochem Biophys Res Commun. 2012. PMID: 22960170 Free PMC article.
IGF1R as a Key Target in High Risk, Metastatic Medulloblastoma.
Svalina MN, Kikuchi K, Abraham J, Lal S, Davare MA, Settelmeyer TP, Young MC, Peckham JL, Cho YJ, Michalek JE, Hernandez BS, Berlow NE, Jackson M, Guillaume DJ, Selden NR, Bigner DD, Nazemi KJ, Green SC, Corless CL, Gultekin S, Mansoor A, Rubin BP, Woltjer R, Keller C. Svalina MN, et al. Among authors: abraham j. Sci Rep. 2016 Jun 3;6:27012. doi: 10.1038/srep27012. Sci Rep. 2016. PMID: 27255663 Free PMC article.
Dynamic and nuclear expression of PDGFRα and IGF-1R in alveolar Rhabdomyosarcoma.
Aslam MI, Hettmer S, Abraham J, Latocha D, Soundararajan A, Huang ET, Goros MW, Michalek JE, Wang S, Mansoor A, Druker BJ, Wagers AJ, Tyner JW, Keller C. Aslam MI, et al. Among authors: abraham j. Mol Cancer Res. 2013 Nov;11(11):1303-13. doi: 10.1158/1541-7786.MCR-12-0598. Epub 2013 Aug 8. Mol Cancer Res. 2013. PMID: 23928059 Free PMC article.
Lineage of origin in rhabdomyosarcoma informs pharmacological response.
Abraham J, Nuñez-Álvarez Y, Hettmer S, Carrió E, Chen HI, Nishijo K, Huang ET, Prajapati SI, Walker RL, Davis S, Rebeles J, Wiebush H, McCleish AT, Hampton ST, Bjornson CR, Brack AS, Wagers AJ, Rando TA, Capecchi MR, Marini FC, Ehler BR, Zarzabal LA, Goros MW, Michalek JE, Meltzer PS, Langenau DM, LeGallo RD, Mansoor A, Chen Y, Suelves M, Rubin BP, Keller C. Abraham J, et al. Genes Dev. 2014 Jul 15;28(14):1578-91. doi: 10.1101/gad.238733.114. Genes Dev. 2014. PMID: 25030697 Free PMC article.
2,028 results