Steppan J - Search Results

1

Upregulation of arginase-II contributes to decreased age-related myocardial contractile reserve.

Khan M, Steppan J, Schuleri KH, Ryoo S, Tuday E, Bugaj L, Santhanam L, Berkowitz T, Nyhan D, Shoukas AA, Berkowitz DE. Khan M, et al. Among authors: steppan j. Eur J Appl Physiol. 2012 Aug;112(8):2933-41. doi: 10.1007/s00421-011-2257-9. Epub 2011 Dec 8. Eur J Appl Physiol. 2012. PMID: 22160208

2

Knockdown of arginase I restores NO signaling in the vasculature of old rats.

White AR, Ryoo S, Li D, Champion HC, Steppan J, Wang D, Nyhan D, Shoukas AA, Hare JM, Berkowitz DE. White AR, et al. Among authors: steppan j. Hypertension. 2006 Feb;47(2):245-51. doi: 10.1161/01.HYP.0000198543.34502.d7. Epub 2005 Dec 27. Hypertension. 2006. PMID: 16380531

3

Arginase modulates myocardial contractility by a nitric oxide synthase 1-dependent mechanism.

Steppan J, Ryoo S, Schuleri KH, Gregg C, Hasan RK, White AR, Bugaj LJ, Khan M, Santhanam L, Nyhan D, Shoukas AA, Hare JM, Berkowitz DE. Steppan J, et al. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4759-64. doi: 10.1073/pnas.0506589103. Epub 2006 Mar 13. Proc Natl Acad Sci U S A. 2006. PMID: 16537391 Free PMC article.

4

β2-adrenergic receptor-coupled phosphoinositide 3-kinase constrains cAMP-dependent increases in cardiac inotropy through phosphodiesterase 4 activation.

Gregg CJ, Steppan J, Gonzalez DR, Champion HC, Phan AC, Nyhan D, Shoukas AA, Hare JM, Barouch LA, Berkowitz DE. Gregg CJ, et al. Among authors: steppan j. Anesth Analg. 2010 Oct;111(4):870-7. doi: 10.1213/ANE.0b013e3181ee8312. Epub 2010 Aug 12. Anesth Analg. 2010. PMID: 20705779

5

Vascular stiffness and increased pulse pressure in the aging cardiovascular system.

Steppan J, Barodka V, Berkowitz DE, Nyhan D. Steppan J, et al. Cardiol Res Pract. 2011;2011:263585. doi: 10.4061/2011/263585. Epub 2011 Aug 2. Cardiol Res Pract. 2011. PMID: 21845218 Free PMC article.

6

Hydrogen sulfide as endothelium-derived hyperpolarizing factor sulfhydrates potassium channels.

Mustafa AK, Sikka G, Gazi SK, Steppan J, Jung SM, Bhunia AK, Barodka VM, Gazi FK, Barrow RK, Wang R, Amzel LM, Berkowitz DE, Snyder SH. Mustafa AK, et al. Among authors: steppan j. Circ Res. 2011 Nov 11;109(11):1259-68. doi: 10.1161/CIRCRESAHA.111.240242. Epub 2011 Oct 6. Circ Res. 2011. PMID: 21980127 Free PMC article.

7

Chronic oral administration of the arginase inhibitor 2(S)-amino-6-boronohexanoic acid (ABH) improves erectile function in aged rats.

Segal R, Hannan JL, Liu X, Kutlu O, Burnett AL, Champion HC, Kim JH, Steppan J, Berkowitz DE, Bivalacqua TJ. Segal R, et al. Among authors: steppan j. J Androl. 2012 Nov-Dec;33(6):1169-75. doi: 10.2164/jandrol.111.015834. Epub 2012 Apr 5. J Androl. 2012. PMID: 22492840 Free PMC article.

8

Alagebrium in combination with exercise ameliorates age-associated ventricular and vascular stiffness.

Steppan J, Tran H, Benjo AM, Pellakuru L, Barodka V, Ryoo S, Nyhan SM, Lussman C, Gupta G, White AR, Daher JP, Shoukas AA, Levine BD, Berkowitz DE. Steppan J, et al. Exp Gerontol. 2012 Aug;47(8):565-72. doi: 10.1016/j.exger.2012.04.006. Epub 2012 Apr 28. Exp Gerontol. 2012. PMID: 22569357 Free PMC article.

9

Vasopressin-mediated enhancement of adrenergic vasoconstriction involves both the tyrosine kinase and the protein kinase C pathways.

Steppan J, Nyhan SM, Sikka G, Uribe J, Ahuja A, White AR, Shoukas AA, Berkowitz DE. Steppan J, et al. Anesth Analg. 2012 Dec;115(6):1290-5. doi: 10.1213/ANE.0b013e3182691c11. Epub 2012 Aug 10. Anesth Analg. 2012. PMID: 22886838

10

Interleukin 10 knockout frail mice develop cardiac and vascular dysfunction with increased age.

Sikka G, Miller KL, Steppan J, Pandey D, Jung SM, Fraser CD 3rd, Ellis C, Ross D, Vandegaer K, Bedja D, Gabrielson K, Walston JD, Berkowitz DE, Barouch LA. Sikka G, et al. Among authors: steppan j. Exp Gerontol. 2013 Feb;48(2):128-35. doi: 10.1016/j.exger.2012.11.001. Epub 2012 Nov 13. Exp Gerontol. 2013. PMID: 23159957 Free PMC article.

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