van den Heuvel J - Search Results

1

Streamlining homogeneous glycoprotein production for biophysical and structural applications by targeted cell line development.

Wilke S, Groebe L, Maffenbeier V, Jäger V, Gossen M, Josewski J, Duda A, Polle L, Owens RJ, Wirth D, Heinz DW, van den Heuvel J, Büssow K. Wilke S, et al. Among authors: van den heuvel j. PLoS One. 2011;6(12):e27829. doi: 10.1371/journal.pone.0027829. Epub 2011 Dec 9. PLoS One. 2011. PMID: 22174749 Free PMC article.

2

Crystal structure of 5-aminolevulinate synthase, the first enzyme of heme biosynthesis, and its link to XLSA in humans.

Astner I, Schulze JO, van den Heuvel J, Jahn D, Schubert WD, Heinz DW. Astner I, et al. Among authors: van den heuvel j. EMBO J. 2005 Sep 21;24(18):3166-77. doi: 10.1038/sj.emboj.7600792. Epub 2005 Aug 25. EMBO J. 2005. PMID: 16121195 Free PMC article.

3

Extending the host range of Listeria monocytogenes by rational protein design.

Wollert T, Pasche B, Rochon M, Deppenmeier S, van den Heuvel J, Gruber AD, Heinz DW, Lengeling A, Schubert WD. Wollert T, et al. Among authors: van den heuvel j. Cell. 2007 Jun 1;129(5):891-902. doi: 10.1016/j.cell.2007.03.049. Cell. 2007. PMID: 17540170 Free article.

4

Structure of the human receptor tyrosine kinase met in complex with the Listeria invasion protein InlB.

Niemann HH, Jäger V, Butler PJ, van den Heuvel J, Schmidt S, Ferraris D, Gherardi E, Heinz DW. Niemann HH, et al. Among authors: van den heuvel j. Cell. 2007 Jul 27;130(2):235-46. doi: 10.1016/j.cell.2007.05.037. Cell. 2007. PMID: 17662939 Free article.

5

Structure of the type III secretion recognition protein YscU from Yersinia enterocolitica.

Wiesand U, Sorg I, Amstutz M, Wagner S, van den Heuvel J, Lührs T, Cornelis GR, Heinz DW. Wiesand U, et al. Among authors: van den heuvel j. J Mol Biol. 2009 Jan 23;385(3):854-66. doi: 10.1016/j.jmb.2008.10.034. Epub 2008 Oct 19. J Mol Biol. 2009. PMID: 18976663

6

Glycoprotein production for structure analysis with stable, glycosylation mutant CHO cell lines established by fluorescence-activated cell sorting.

Wilke S, Krausze J, Gossen M, Groebe L, Jäger V, Gherardi E, van den Heuvel J, Büssow K. Wilke S, et al. Among authors: van den heuvel j. Protein Sci. 2010 Jun;19(6):1264-71. doi: 10.1002/pro.390. Protein Sci. 2010. PMID: 20512979 Free PMC article.

7

High affinity peptide inhibitors of the hepatitis C virus NS3-4A protease refractory to common resistant mutants.

Kügler J, Schmelz S, Gentzsch J, Haid S, Pollmann E, van den Heuvel J, Franke R, Pietschmann T, Heinz DW, Collins J. Kügler J, et al. Among authors: van den heuvel j. J Biol Chem. 2012 Nov 9;287(46):39224-32. doi: 10.1074/jbc.M112.393843. Epub 2012 Sep 10. J Biol Chem. 2012. PMID: 22965230 Free PMC article.

8

Multi-host expression system for recombinant production of challenging proteins.

Meyer S, Lorenz C, Baser B, Wördehoff M, Jäger V, van den Heuvel J. Meyer S, et al. Among authors: van den heuvel j. PLoS One. 2013 Jul 17;8(7):e68674. doi: 10.1371/journal.pone.0068674. Print 2013. PLoS One. 2013. PMID: 23874717 Free PMC article.

9

A method for specifically targeting two independent genomic integration sites for co-expression of genes in CHO cells.

Baser B, Spehr J, Büssow K, van den Heuvel J. Baser B, et al. Among authors: van den heuvel j. Methods. 2016 Feb 15;95:3-12. doi: 10.1016/j.ymeth.2015.11.022. Epub 2015 Dec 2. Methods. 2016. PMID: 26658354 Free article.

10

Identification of Essential Genetic Baculoviral Elements for Recombinant Protein Expression by Transactivation in Sf21 Insect Cells.

Bleckmann M, Schürig M, Chen FF, Yen ZZ, Lindemann N, Meyer S, Spehr J, van den Heuvel J. Bleckmann M, et al. Among authors: van den heuvel j. PLoS One. 2016 Mar 2;11(3):e0149424. doi: 10.1371/journal.pone.0149424. eCollection 2016. PLoS One. 2016. PMID: 26934632 Free PMC article.

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