Willems E - Search Results

1

Wnt inhibition correlates with human embryonic stem cell cardiomyogenesis: a structure-activity relationship study based on inhibitors for the Wnt response.

Lanier M, Schade D, Willems E, Tsuda M, Spiering S, Kalisiak J, Mercola M, Cashman JR. Lanier M, et al. Among authors: willems e. J Med Chem. 2012 Jan 26;55(2):697-708. doi: 10.1021/jm2010223. Epub 2012 Jan 13. J Med Chem. 2012. PMID: 22191557 Free PMC article.

2

Synthesis and SAR of b-annulated 1,4-dihydropyridines define cardiomyogenic compounds as novel inhibitors of TGFβ signaling.

Schade D, Lanier M, Willems E, Okolotowicz K, Bushway P, Wahlquist C, Gilley C, Mercola M, Cashman JR. Schade D, et al. Among authors: willems e. J Med Chem. 2012 Nov 26;55(22):9946-57. doi: 10.1021/jm301144g. Epub 2012 Nov 6. J Med Chem. 2012. PMID: 23130626 Free PMC article.

3

Small-molecule inhibitors of the Wnt pathway potently promote cardiomyocytes from human embryonic stem cell-derived mesoderm.

Willems E, Spiering S, Davidovics H, Lanier M, Xia Z, Dawson M, Cashman J, Mercola M. Willems E, et al. Circ Res. 2011 Aug 5;109(4):360-4. doi: 10.1161/CIRCRESAHA.111.249540. Epub 2011 Jul 7. Circ Res. 2011. PMID: 21737789 Free PMC article.

4

Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells.

Willems E, Cabral-Teixeira J, Schade D, Cai W, Reeves P, Bushway PJ, Lanier M, Walsh C, Kirchhausen T, Izpisua Belmonte JC, Cashman J, Mercola M. Willems E, et al. Cell Stem Cell. 2012 Aug 3;11(2):242-52. doi: 10.1016/j.stem.2012.04.025. Cell Stem Cell. 2012. PMID: 22862949 Free PMC article.

5

Natural and synthetic regulators of embryonic stem cell cardiogenesis.

Willems E, Bushway PJ, Mercola M. Willems E, et al. Pediatr Cardiol. 2009 Jul;30(5):635-42. doi: 10.1007/s00246-009-9409-2. Epub 2009 Mar 25. Pediatr Cardiol. 2009. PMID: 19319460 Free PMC article.

6

A chemical biology approach to myocardial regeneration.

Willems E, Lanier M, Forte E, Lo F, Cashman J, Mercola M. Willems E, et al. J Cardiovasc Transl Res. 2011 Jun;4(3):340-50. doi: 10.1007/s12265-011-9270-6. Epub 2011 Mar 22. J Cardiovasc Transl Res. 2011. PMID: 21424858 Free PMC article. Review.

7

Coordinate Nodal and BMP inhibition directs Baf60c-dependent cardiomyocyte commitment.

Cai W, Albini S, Wei K, Willems E, Guzzo RM, Tsuda M, Giordani L, Spiering S, Kurian L, Yeo GW, Puri PL, Mercola M. Cai W, et al. Among authors: willems e. Genes Dev. 2013 Nov 1;27(21):2332-44. doi: 10.1101/gad.225144.113. Genes Dev. 2013. PMID: 24186978 Free PMC article.

8

Reprogramming the cardiac field.

Willems E, Mercola M. Willems E, et al. Circ Res. 2014 Jan 31;114(3):409-11. doi: 10.1161/CIRCRESAHA.113.302946. Circ Res. 2014. PMID: 24481840 Free PMC article.

9

High content screening for modulators of cardiac differentiation in human pluripotent stem cells.

Spiering S, Davidovics H, Bushway PJ, Mercola M, Willems E. Spiering S, et al. Among authors: willems e. Methods Mol Biol. 2015;1263:43-61. doi: 10.1007/978-1-4939-2269-7_4. Methods Mol Biol. 2015. PMID: 25618335 Free PMC article.

10

Cholesterol-derived glucocorticoids control early fate specification in embryonic stem cells.

Cabral-Teixeira J, Martinez-Fernandez A, Cai W, Terzic A, Mercola M, Willems E. Cabral-Teixeira J, et al. Among authors: willems e. Stem Cell Res. 2015 Jul;15(1):88-95. doi: 10.1016/j.scr.2015.04.010. Epub 2015 May 14. Stem Cell Res. 2015. PMID: 26024790 Free PMC article.

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