Vainio P - Search Results

1

Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins.

Vainio P, Lehtinen L, Mirtti T, Hilvo M, Seppänen-Laakso T, Virtanen J, Sankila A, Nordling S, Lundin J, Rannikko A, Orešič M, Kallioniemi O, Iljin K. Vainio P, et al. Oncotarget. 2011 Dec;2(12):1176-90. doi: 10.18632/oncotarget.397. Oncotarget. 2011. PMID: 22202492 Free PMC article.

2

Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues.

Kilpinen S, Autio R, Ojala K, Iljin K, Bucher E, Sara H, Pisto T, Saarela M, Skotheim RI, Björkman M, Mpindi JP, Haapa-Paananen S, Vainio P, Edgren H, Wolf M, Astola J, Nees M, Hautaniemi S, Kallioniemi O. Kilpinen S, et al. Among authors: vainio p. Genome Biol. 2008;9(9):R139. doi: 10.1186/gb-2008-9-9-r139. Epub 2008 Sep 19. Genome Biol. 2008. PMID: 18803840 Free PMC article.

3

High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth.

Iljin K, Ketola K, Vainio P, Halonen P, Kohonen P, Fey V, Grafström RC, Perälä M, Kallioniemi O. Iljin K, et al. Among authors: vainio p. Clin Cancer Res. 2009 Oct 1;15(19):6070-8. doi: 10.1158/1078-0432.CCR-09-1035. Epub 2009 Sep 29. Clin Cancer Res. 2009. PMID: 19789329

4

FZD4 as a mediator of ERG oncogene-induced WNT signaling and epithelial-to-mesenchymal transition in human prostate cancer cells.

Gupta S, Iljin K, Sara H, Mpindi JP, Mirtti T, Vainio P, Rantala J, Alanen K, Nees M, Kallioniemi O. Gupta S, et al. Among authors: vainio p. Cancer Res. 2010 Sep 1;70(17):6735-45. doi: 10.1158/0008-5472.CAN-10-0244. Epub 2010 Aug 16. Cancer Res. 2010. PMID: 20713528

5

Monensin is a potent inducer of oxidative stress and inhibitor of androgen signaling leading to apoptosis in prostate cancer cells.

Ketola K, Vainio P, Fey V, Kallioniemi O, Iljin K. Ketola K, et al. Among authors: vainio p. Mol Cancer Ther. 2010 Dec;9(12):3175-85. doi: 10.1158/1535-7163.MCT-10-0368. Mol Cancer Ther. 2010. PMID: 21159605

6

Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer.

Vainio P, Gupta S, Ketola K, Mirtti T, Mpindi JP, Kohonen P, Fey V, Perälä M, Smit F, Verhaegh G, Schalken J, Alanen KA, Kallioniemi O, Iljin K. Vainio P, et al. Am J Pathol. 2011 Feb;178(2):525-36. doi: 10.1016/j.ajpath.2010.10.002. Am J Pathol. 2011. PMID: 21281786 Free PMC article.

7

GTI: a novel algorithm for identifying outlier gene expression profiles from integrated microarray datasets.

Mpindi JP, Sara H, Haapa-Paananen S, Kilpinen S, Pisto T, Bucher E, Ojala K, Iljin K, Vainio P, Björkman M, Gupta S, Kohonen P, Nees M, Kallioniemi O. Mpindi JP, et al. Among authors: vainio p. PLoS One. 2011 Feb 18;6(2):e17259. doi: 10.1371/journal.pone.0017259. PLoS One. 2011. PMID: 21365010 Free PMC article.

8

Integrative genomic, transcriptomic, and RNAi analysis indicates a potential oncogenic role for FAM110B in castration-resistant prostate cancer.

Vainio P, Wolf M, Edgren H, He T, Kohonen P, Mpindi JP, Smit F, Verhaegh G, Schalken J, Perälä M, Iljin K, Kallioniemi O. Vainio P, et al. Prostate. 2012 May 15;72(7):789-802. doi: 10.1002/pros.21487. Epub 2011 Sep 14. Prostate. 2012. PMID: 21919029

9

15-Hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition, and promotes cell migration in cultured breast cancer cells.

Lehtinen L, Vainio P, Wikman H, Reemts J, Hilvo M, Issa R, Pollari S, Brandt B, Oresic M, Pantel K, Kallioniemi O, Iljin K. Lehtinen L, et al. Among authors: vainio p. J Pathol. 2012 Mar;226(4):674-86. doi: 10.1002/path.3956. Epub 2012 Jan 17. J Pathol. 2012. PMID: 22072156

10

High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer.

Vainio P, Mpindi JP, Kohonen P, Fey V, Mirtti T, Alanen KA, Perälä M, Kallioniemi O, Iljin K. Vainio P, et al. PLoS One. 2012;7(6):e39801. doi: 10.1371/journal.pone.0039801. Epub 2012 Jun 28. PLoS One. 2012. PMID: 22761906 Free PMC article.

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