Salazar DE - Search Results

1

The use of modeling and simulation to guide clinical development of olmesartan medoxomil in pediatric subjects.

Salazar DE, Song SH, Shi J, Rohatagi S, Heyrman R, Wada DR, Carrothers TJ. Salazar DE, et al. Clin Pharmacol Ther. 2012 Feb;91(2):250-6. doi: 10.1038/clpt.2011.220. Epub 2011 Dec 28. Clin Pharmacol Ther. 2012. PMID: 22205195

2

Evaluation of population pharmacokinetics and exposure-response relationship with coadministration of amlodipine besylate and olmesartan medoxomil.

Rohatagi S, Carrothers TJ, Kshirsagar S, Khariton T, Lee J, Salazar D. Rohatagi S, et al. J Clin Pharmacol. 2008 Jul;48(7):823-36. doi: 10.1177/0091270008317847. Epub 2008 May 19. J Clin Pharmacol. 2008. PMID: 18490496 Clinical Trial.

3

Predictive population pharmacokinetic/pharmacodynamic model for a novel COX-2 inhibitor.

Rohatagi S, Kastrissios H, Gao Y, Zhang N, Xu J, Moberly J, Wada R, Yoshihara K, Takahashi M, Truitt K, Salazar D. Rohatagi S, et al. J Clin Pharmacol. 2007 Mar;47(3):358-70. doi: 10.1177/0091270006296152. J Clin Pharmacol. 2007. PMID: 17322148

4

Pharmacokinetics of amlodipine and olmesartan after administration of amlodipine besylate and olmesartan medoxomil in separate dosage forms and as a fixed-dose combination.

Rohatagi S, Lee J, Shenouda M, Haworth S, Bathala MS, Allison M, Rubets I, Heyrman R, Noveck R, Salazar DE. Rohatagi S, et al. Among authors: salazar de. J Clin Pharmacol. 2008 Nov;48(11):1309-22. doi: 10.1177/0091270008322176. J Clin Pharmacol. 2008. PMID: 18974285

5

Modelling and simulation of edoxaban exposure and response relationships in patients with atrial fibrillation.

Salazar DE, Mendell J, Kastrissios H, Green M, Carrothers TJ, Song S, Patel I, Bocanegra TS, Antman EM, Giugliano RP, Kunitada S, Dornseif B, Shi M, Tachibana M, Zhou S, Rohatagi S. Salazar DE, et al. Thromb Haemost. 2012 May;107(5):925-36. doi: 10.1160/TH11-08-0566. Epub 2012 Mar 8. Thromb Haemost. 2012. PMID: 22398655 Clinical Trial.

6

Model-Supported Development of CS-8635: A Fixed-Dose Combination of Olmesartan, Amlodipine, and Hydrochlorothiazide.

Song S, Carrothers TJ, Moore H, Green M, Miller R, Rohatagi S, Lee J, Wang A, Melino M, Patel M, Heyrman R, Salazar DE. Song S, et al. Among authors: salazar de. Clin Pharmacol Drug Dev. 2013 Apr;2(2):103-12. doi: 10.1002/cpdd.17. Epub 2013 Mar 16. Clin Pharmacol Drug Dev. 2013. PMID: 27121665

7

Model-based development of a PPARgamma agonist, rivoglitazone, to aid dose selection and optimize clinical trial designs.

Rohatagi S, Carrothers TJ, Jin J, Jusko WJ, Khariton T, Walker J, Truitt K, Salazar DE. Rohatagi S, et al. Among authors: salazar de. J Clin Pharmacol. 2008 Dec;48(12):1420-9. doi: 10.1177/0091270008323260. Epub 2008 Oct 20. J Clin Pharmacol. 2008. PMID: 18936283 Clinical Trial.

8

Quantitative structure-property relationships modeling to predict in vitro and in vivo binding of drugs to the bile sequestrant, colesevelam (Welchol).

Walker JR, Brown K, Rohatagi S, Bathala MS, Xu C, Wickremasingha PK, Salazar DE, Mager DE. Walker JR, et al. Among authors: salazar de. J Clin Pharmacol. 2009 Oct;49(10):1185-95. doi: 10.1177/0091270009340783. J Clin Pharmacol. 2009. PMID: 19783712

9

Correlation of inhibition of platelet aggregation with cardiovascular and bleeding outcomes in acute coronary syndromes.

Wada R, Rohatagi S, Small D, Winters KJ, Salazar DE. Wada R, et al. Among authors: salazar de. J Clin Pharmacol. 2010 Aug;50(8):904-13. doi: 10.1177/0091270009353606. Epub 2010 Feb 10. J Clin Pharmacol. 2010. PMID: 20147617

10

Pharmacokinetics of olmesartan medoxomil in pediatric patients with hypertension.

Wells TG, Blowey DL, Sullivan JE, Blumer J, Sherbotie JR, Song S, Rohatagi S, Heyrman R, Salazar DE. Wells TG, et al. Among authors: salazar de. Paediatr Drugs. 2012 Dec 1;14(6):401-9. doi: 10.2165/11631450-000000000-00000. Paediatr Drugs. 2012. PMID: 22880942 Clinical Trial.

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