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Humanized mice for modeling human infectious disease: challenges, progress, and outlook.
Legrand N, Ploss A, Balling R, Becker PD, Borsotti C, Brezillon N, Debarry J, de Jong Y, Deng H, Di Santo JP, Eisenbarth S, Eynon E, Flavell RA, Guzman CA, Huntington ND, Kremsdorf D, Manns MP, Manz MG, Mention JJ, Ott M, Rathinam C, Rice CM, Rongvaux A, Stevens S, Spits H, Strick-Marchand H, Takizawa H, van Lent AU, Wang C, Weijer K, Willinger T, Ziegler P. Legrand N, et al. Among authors: takizawa h. Cell Host Microbe. 2009 Jul 23;6(1):5-9. doi: 10.1016/j.chom.2009.06.006. Cell Host Microbe. 2009. PMID: 19616761 Free PMC article. Review.
Human IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lung.
Willinger T, Rongvaux A, Takizawa H, Yancopoulos GD, Valenzuela DM, Murphy AJ, Auerbach W, Eynon EE, Stevens S, Manz MG, Flavell RA. Willinger T, et al. Among authors: takizawa h. Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2390-5. doi: 10.1073/pnas.1019682108. Epub 2011 Jan 24. Proc Natl Acad Sci U S A. 2011. PMID: 21262803 Free PMC article.
Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo.
Rongvaux A, Willinger T, Takizawa H, Rathinam C, Auerbach W, Murphy AJ, Valenzuela DM, Yancopoulos GD, Eynon EE, Stevens S, Manz MG, Flavell RA. Rongvaux A, et al. Among authors: takizawa h. Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2378-83. doi: 10.1073/pnas.1019524108. Epub 2011 Jan 24. Proc Natl Acad Sci U S A. 2011. PMID: 21262827 Free PMC article.
Dynamic regulation of hematopoietic stem cell cycling.
Takizawa H, Manz MG. Takizawa H, et al. Cell Cycle. 2011 Jul 15;10(14):2246-7. doi: 10.4161/cc.10.14.16197. Epub 2011 Jul 15. Cell Cycle. 2011. PMID: 21670591 No abstract available.
Transgenic expression of human signal regulatory protein alpha in Rag2-/-gamma(c)-/- mice improves engraftment of human hematopoietic cells in humanized mice.
Strowig T, Rongvaux A, Rathinam C, Takizawa H, Borsotti C, Philbrick W, Eynon EE, Manz MG, Flavell RA. Strowig T, et al. Among authors: takizawa h. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13218-23. doi: 10.1073/pnas.1109769108. Epub 2011 Jul 25. Proc Natl Acad Sci U S A. 2011. PMID: 21788509 Free PMC article.
942 results