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Page 1
Creating stable stem regions for loop elongation in Fcabs - insights from combining yeast surface display, in silico loop reconstruction and molecular dynamics simulations.
Hasenhindl C, Lai B, Delgado J, Traxlmayr MW, Stadlmayr G, Rüker F, Serrano L, Oostenbrink C, Obinger C. Hasenhindl C, et al. Biochim Biophys Acta. 2014 Sep;1844(9):1530-40. doi: 10.1016/j.bbapap.2014.04.020. Epub 2014 May 2. Biochim Biophys Acta. 2014. PMID: 24792385 Free PMC article.
Construction of pH-sensitive Her2-binding IgG1-Fc by directed evolution.
Traxlmayr MW, Lobner E, Hasenhindl C, Stadlmayr G, Oostenbrink C, Rüker F, Obinger C. Traxlmayr MW, et al. Among authors: hasenhindl c. Biotechnol J. 2014 Aug;9(8):1013-22. doi: 10.1002/biot.201300483. Biotechnol J. 2014. PMID: 24964247 Free PMC article.
Engineered IgG1-Fc--one fragment to bind them all.
Lobner E, Traxlmayr MW, Obinger C, Hasenhindl C. Lobner E, et al. Among authors: hasenhindl c. Immunol Rev. 2016 Mar;270(1):113-31. doi: 10.1111/imr.12385. Immunol Rev. 2016. PMID: 26864108 Free PMC article. Review.
Fcab-HER2 Interaction: a Ménage à Trois. Lessons from X-Ray and Solution Studies.
Lobner E, Humm AS, Göritzer K, Mlynek G, Puchinger MG, Hasenhindl C, Rüker F, Traxlmayr MW, Djinović-Carugo K, Obinger C. Lobner E, et al. Among authors: hasenhindl c. Structure. 2017 Jun 6;25(6):878-889.e5. doi: 10.1016/j.str.2017.04.014. Epub 2017 May 18. Structure. 2017. PMID: 28528777 Free article.
Design of a colicin E7 based chimeric zinc-finger nuclease.
Németh E, Schilli GK, Nagy G, Hasenhindl C, Gyurcsik B, Oostenbrink C. Németh E, et al. Among authors: hasenhindl c. J Comput Aided Mol Des. 2014 Aug;28(8):841-50. doi: 10.1007/s10822-014-9765-8. Epub 2014 Jun 22. J Comput Aided Mol Des. 2014. PMID: 24952471 Free PMC article.
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