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A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer.
Stauber RH, Knauer SK, Habtemichael N, Bier C, Unruhe B, Weisheit S, Spange S, Nonnenmacher F, Fetz V, Ginter T, Reichardt S, Liebmann C, Schneider G, Krämer OH. Stauber RH, et al. Among authors: knauer sk. Oncotarget. 2012 Jan;3(1):31-43. doi: 10.18632/oncotarget.430. Oncotarget. 2012. PMID: 22289787 Free PMC article.
Acetylation of Stat1 modulates NF-kappaB activity.
Krämer OH, Baus D, Knauer SK, Stein S, Jäger E, Stauber RH, Grez M, Pfitzner E, Heinzel T. Krämer OH, et al. Among authors: knauer sk. Genes Dev. 2006 Feb 15;20(4):473-85. doi: 10.1101/gad.364306. Genes Dev. 2006. PMID: 16481475 Free PMC article.
Nuclear export is essential for the tumor-promoting activity of survivin.
Knauer SK, Krämer OH, Knösel T, Engels K, Rödel F, Kovács AF, Dietmaier W, Klein-Hitpass L, Habtemichael N, Schweitzer A, Brieger J, Rödel C, Mann W, Petersen I, Heinzel T, Stauber RH. Knauer SK, et al. FASEB J. 2007 Jan;21(1):207-16. doi: 10.1096/fj.06-5741com. Epub 2006 Nov 10. FASEB J. 2007. PMID: 17099069
141 results