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The histone deacetylase inhibitor valproic acid lessens NK cell action against oncolytic virus-infected glioblastoma cells by inhibition of STAT5/T-BET signaling and generation of gamma interferon.
Alvarez-Breckenridge CA, Yu J, Price R, Wei M, Wang Y, Nowicki MO, Ha YP, Bergin S, Hwang C, Fernandez SA, Kaur B, Caligiuri MA, Chiocca EA. Alvarez-Breckenridge CA, et al. Among authors: chiocca ea. J Virol. 2012 Apr;86(8):4566-77. doi: 10.1128/JVI.05545-11. Epub 2012 Feb 8. J Virol. 2012. PMID: 22318143 Free PMC article.
Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses.
Fulci G, Breymann L, Gianni D, Kurozomi K, Rhee SS, Yu J, Kaur B, Louis DN, Weissleder R, Caligiuri MA, Chiocca EA. Fulci G, et al. Among authors: chiocca ea. Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12873-8. doi: 10.1073/pnas.0605496103. Epub 2006 Aug 14. Proc Natl Acad Sci U S A. 2006. PMID: 16908838 Free PMC article.
Personalizing oncolytic virotherapy?
Kaur B, Chiocca EA. Kaur B, et al. Among authors: chiocca ea. Mol Ther. 2007 Jan;15(1):6-7. doi: 10.1038/sj.mt.6300056. Mol Ther. 2007. PMID: 17164767 Free article. No abstract available.
Oncolytic viruses driven by tumor-specific promoters.
Hardcastle J, Kurozumi K, Chiocca EA, Kaur B. Hardcastle J, et al. Among authors: chiocca ea. Curr Cancer Drug Targets. 2007 Mar;7(2):181-9. doi: 10.2174/156800907780058880. Curr Cancer Drug Targets. 2007. PMID: 17346110 Review.
NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors.
Alvarez-Breckenridge CA, Yu J, Price R, Wojton J, Pradarelli J, Mao H, Wei M, Wang Y, He S, Hardcastle J, Fernandez SA, Kaur B, Lawler SE, Vivier E, Mandelboim O, Moretta A, Caligiuri MA, Chiocca EA. Alvarez-Breckenridge CA, et al. Among authors: chiocca ea. Nat Med. 2012 Dec;18(12):1827-34. doi: 10.1038/nm.3013. Epub 2012 Nov 25. Nat Med. 2012. PMID: 23178246 Free PMC article.
457 results