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Page 1
Pleiotropic role for MYCN in medulloblastoma.
Swartling FJ, Grimmer MR, Hackett CS, Northcott PA, Fan QW, Goldenberg DD, Lau J, Masic S, Nguyen K, Yakovenko S, Zhe XN, Gilmer HC, Collins R, Nagaoka M, Phillips JJ, Jenkins RB, Tihan T, Vandenberg SR, James CD, Tanaka K, Taylor MD, Weiss WA, Chesler L. Swartling FJ, et al. Among authors: taylor md. Genes Dev. 2010 May 15;24(10):1059-72. doi: 10.1101/gad.1907510. Genes Dev. 2010. PMID: 20478998 Free PMC article.
PCDH10 is a candidate tumour suppressor gene in medulloblastoma.
Bertrand KC, Mack SC, Northcott PA, Garzia L, Dubuc A, Pfister SM, Rutka JT, Weiss WA, Taylor MD. Bertrand KC, et al. Among authors: taylor md. Childs Nerv Syst. 2011 Aug;27(8):1243-9. doi: 10.1007/s00381-011-1486-x. Epub 2011 May 20. Childs Nerv Syst. 2011. PMID: 21597995
Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct.
Northcott PA, Hielscher T, Dubuc A, Mack S, Shih D, Remke M, Al-Halabi H, Albrecht S, Jabado N, Eberhart CG, Grajkowska W, Weiss WA, Clifford SC, Bouffet E, Rutka JT, Korshunov A, Pfister S, Taylor MD. Northcott PA, et al. Among authors: taylor md. Acta Neuropathol. 2011 Aug;122(2):231-40. doi: 10.1007/s00401-011-0846-7. Epub 2011 Jun 17. Acta Neuropathol. 2011. PMID: 21681522 Free PMC article.
Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma.
Witt H, Mack SC, Ryzhova M, Bender S, Sill M, Isserlin R, Benner A, Hielscher T, Milde T, Remke M, Jones DT, Northcott PA, Garzia L, Bertrand KC, Wittmann A, Yao Y, Roberts SS, Massimi L, Van Meter T, Weiss WA, Gupta N, Grajkowska W, Lach B, Cho YJ, von Deimling A, Kulozik AE, Witt O, Bader GD, Hawkins CE, Tabori U, Guha A, Rutka JT, Lichter P, Korshunov A, Taylor MD, Pfister SM. Witt H, et al. Among authors: taylor md. Cancer Cell. 2011 Aug 16;20(2):143-57. doi: 10.1016/j.ccr.2011.07.007. Cancer Cell. 2011. PMID: 21840481 Free PMC article.
CXCR4 activation defines a new subgroup of Sonic hedgehog-driven medulloblastoma.
Sengupta R, Dubuc A, Ward S, Yang L, Northcott P, Woerner BM, Kroll K, Luo J, Taylor MD, Wechsler-Reya RJ, Rubin JB. Sengupta R, et al. Among authors: taylor md. Cancer Res. 2012 Jan 1;72(1):122-32. doi: 10.1158/0008-5472.CAN-11-1701. Epub 2011 Nov 3. Cancer Res. 2012. PMID: 22052462 Free PMC article.
Molecular subgroups of medulloblastoma: the current consensus.
Taylor MD, Northcott PA, Korshunov A, Remke M, Cho YJ, Clifford SC, Eberhart CG, Parsons DW, Rutkowski S, Gajjar A, Ellison DW, Lichter P, Gilbertson RJ, Pomeroy SL, Kool M, Pfister SM. Taylor MD, et al. Acta Neuropathol. 2012 Apr;123(4):465-72. doi: 10.1007/s00401-011-0922-z. Epub 2011 Dec 2. Acta Neuropathol. 2012. PMID: 22134537 Free PMC article.
Biological and clinical heterogeneity of MYCN-amplified medulloblastoma.
Korshunov A, Remke M, Kool M, Hielscher T, Northcott PA, Williamson D, Pfaff E, Witt H, Jones DT, Ryzhova M, Cho YJ, Wittmann A, Benner A, Weiss WA, von Deimling A, Scheurlen W, Kulozik AE, Clifford SC, Peter Collins V, Westermann F, Taylor MD, Lichter P, Pfister SM. Korshunov A, et al. Among authors: taylor md. Acta Neuropathol. 2012 Apr;123(4):515-27. doi: 10.1007/s00401-011-0918-8. Epub 2011 Dec 9. Acta Neuropathol. 2012. PMID: 22160402
An animal model of MYC-driven medulloblastoma.
Pei Y, Moore CE, Wang J, Tewari AK, Eroshkin A, Cho YJ, Witt H, Korshunov A, Read TA, Sun JL, Schmitt EM, Miller CR, Buckley AF, McLendon RE, Westbrook TF, Northcott PA, Taylor MD, Pfister SM, Febbo PG, Wechsler-Reya RJ. Pei Y, et al. Among authors: taylor md. Cancer Cell. 2012 Feb 14;21(2):155-67. doi: 10.1016/j.ccr.2011.12.021. Cancer Cell. 2012. PMID: 22340590 Free PMC article.
Clonal selection drives genetic divergence of metastatic medulloblastoma.
Wu X, Northcott PA, Dubuc A, Dupuy AJ, Shih DJ, Witt H, Croul S, Bouffet E, Fults DW, Eberhart CG, Garzia L, Van Meter T, Zagzag D, Jabado N, Schwartzentruber J, Majewski J, Scheetz TE, Pfister SM, Korshunov A, Li XN, Scherer SW, Cho YJ, Akagi K, MacDonald TJ, Koster J, McCabe MG, Sarver AL, Collins VP, Weiss WA, Largaespada DA, Collier LS, Taylor MD. Wu X, et al. Among authors: taylor md. Nature. 2012 Feb 15;482(7386):529-33. doi: 10.1038/nature10825. Nature. 2012. PMID: 22343890 Free PMC article.
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